PDF(Pubmed)
Abstract：
UNASSIGNED: Breast cancer is the most common cancer in women and the second leading cause of cancer-related death. Breast cancer manifestations in the head and neck are relatively rare, have greater predilection for the jaws than for soft tissues. Metastasis in the oral cavity account for only 1 to 3 % of all oral malignant lesions. Regardless of the rare occurrence of metastatic lesions to the jaw, it should be taken into consideration in the individuals with a history of malignancy.
METHODS: The article reports a rare case of metastatic lesion of breast cancer to unilateral mandibular ramus region. The 66-year-old female patient was complaining of pain and swelling in the right mandible angle. She was referred to our department by her oncologist with the differential diagnosis of osteonecrosis or metastasis. She had undergone radical mastectomy for invasive lobular carcinoma of the left breast without adjuvant treatment. Oral cavity examination did not reveal the existence of any ulcer or fistula. Based on the patient\'s medical history and paresthesia of the lower lip and chin, the metastatic disease was highly suspected. The patient was referred to her oncologist for chemotherapy treatment before any invasive surgical management.
UNASSIGNED: Breast cancer (BC) is the most common cancer affecting women globally. Bone is the most common site of metastasis in BC patients, with up to 75 % of stage IV BC patients developing skeletal metastasis. The frequent metastatic sites of bone are spine, ribs, sternum, femur, pelvis. Breast carcinoma metastasizes to the jaw bones are uncommon.
CONCLUSIONS: The diagnosis of metastasis to the oral cavity is a significant challenge to the clinician due to the lack of pathognomonic signs and symptoms. The general dentist or dental specialist should maintain a high level of suspicion while dealing patients with a history of cancer.
METHODS: The article reports a rare case of metastatic lesion of breast cancer to unilateral mandibular ramus region. The 66-year-old female patient was complaining of pain and swelling in the right mandible angle. She was referred to our department by her oncologist with the differential diagnosis of osteonecrosis or metastasis. She had undergone radical mastectomy for invasive lobular carcinoma of the left breast without adjuvant treatment. Oral cavity examination did not reveal the existence of any ulcer or fistula. Based on the patient\'s medical history and paresthesia of the lower lip and chin, the metastatic disease was highly suspected. The patient was referred to her oncologist for chemotherapy treatment before any invasive surgical management.
UNASSIGNED: Breast cancer (BC) is the most common cancer affecting women globally. Bone is the most common site of metastasis in BC patients, with up to 75 % of stage IV BC patients developing skeletal metastasis. The frequent metastatic sites of bone are spine, ribs, sternum, femur, pelvis. Breast carcinoma metastasizes to the jaw bones are uncommon.
CONCLUSIONS: The diagnosis of metastasis to the oral cavity is a significant challenge to the clinician due to the lack of pathognomonic signs and symptoms. The general dentist or dental specialist should maintain a high level of suspicion while dealing patients with a history of cancer.
摘要：
乳腺癌是女性中最常见的癌症，也是癌症相关死亡的第二大原因。头颈部的乳腺癌表现相对罕见，对颌骨的偏爱大于对软组织的偏爱。口腔转移仅占所有口腔恶性病变的1-3％。不管颌骨转移性病变的罕见发生，在有恶性肿瘤病史的个体中应考虑这一点.
方法：本文报道一例罕见的乳腺癌单侧下颌支转移灶。这位66岁的女性患者抱怨右下颌骨角度疼痛和肿胀。她的肿瘤科医生将她转诊到我们的部门，以鉴别诊断为骨坏死或转移。她因左乳腺浸润性小叶癌接受了根治术，没有进行辅助治疗。口腔检查未发现任何溃疡或瘘管的存在。根据患者的病史和下唇和下巴的感觉异常，高度怀疑转移性疾病.在进行任何侵入性手术治疗之前，将患者转介给她的肿瘤科医生进行化疗。
乳腺癌（BC）是全球女性最常见的癌症。骨是BC患者最常见的转移部位，高达75％的IV期BC患者发生骨转移。骨的常见转移部位是脊柱，肋骨,胸骨,股骨,骨盆。乳腺癌转移到颌骨并不常见。
结论：由于缺乏病理性体征和症状，口腔转移的诊断对临床医生来说是一个重大挑战。普通牙医或牙科专家在处理有癌症史的患者时应保持高度怀疑。
方法：本文报道一例罕见的乳腺癌单侧下颌支转移灶。这位66岁的女性患者抱怨右下颌骨角度疼痛和肿胀。她的肿瘤科医生将她转诊到我们的部门，以鉴别诊断为骨坏死或转移。她因左乳腺浸润性小叶癌接受了根治术，没有进行辅助治疗。口腔检查未发现任何溃疡或瘘管的存在。根据患者的病史和下唇和下巴的感觉异常，高度怀疑转移性疾病.在进行任何侵入性手术治疗之前，将患者转介给她的肿瘤科医生进行化疗。
乳腺癌（BC）是全球女性最常见的癌症。骨是BC患者最常见的转移部位，高达75％的IV期BC患者发生骨转移。骨的常见转移部位是脊柱，肋骨,胸骨,股骨,骨盆。乳腺癌转移到颌骨并不常见。
结论：由于缺乏病理性体征和症状，口腔转移的诊断对临床医生来说是一个重大挑战。普通牙医或牙科专家在处理有癌症史的患者时应保持高度怀疑。
