关键词: bisphosphonates coccidioidomycosis granulomatous disease hypercalcemia steroids

来  源:   DOI:10.7759/cureus.63977   PDF(Pubmed)

Abstract:
The clinical course and treatment of hypercalcemia from a granulomatous disease in the setting of an infectious etiology, namely disseminated coccidioidomycosis, remains incompletely understood. The mechanism and treatment of hypercalcemia have been documented in most granulomatous disorders, with sarcoidosis being the most well-understood so far. We discuss a case of a patient with a recent diagnosis of disseminated coccidioidomycosis who presented with hypercalcemia despite adequate infection control. The treatment course involved combinatorial-calcitonin, low-dose bisphosphonates, and corticosteroids, which led to a favorable outcome.
摘要:
在感染性病因的背景下,肉芽肿性疾病引起的高钙血症的临床过程和治疗,即播散性球虫菌病,仍然不完全理解。高钙血症的机制和治疗已在大多数肉芽肿性疾病中得到证实,结节病是迄今为止最容易理解的。我们讨论了一例最近诊断为播散性球虫菌病的患者,尽管进行了适当的感染控制,但仍出现高钙血症。治疗过程涉及组合降钙素,低剂量双膦酸盐,和皮质类固醇,这导致了一个有利的结果。
公众号