PDF(Pubmed)
Abstract：
UNASSIGNED: Primary hyperaldosteronism with type 3 autoimmune polyendocrine syndrome was a rare combination of both hyper- and hypoendocrine gland function. Comprehensive treatment including surgery and replacement therapy might be an effective strategy.
UNASSIGNED: Primary aldosteronism (PA) is a common cause of secondary hypertension originating from hormones. Type 3 autoimmune polyendocrine syndrome (APS-3) is characterized by the simultaneous or subsequent occurrence of autoimmune-mediated endocrine gland damage, except for Addison disease. Here we reported an extremely rare case of a 63-year-old woman with PA and APS-3 who initially presented with hypertension (HT). The APS-3 of this patient mainly exhibited type 1 diabetes mellitus (T1DM) and Hashimoto\'s thyroiditis. She underwent the adrenal adenoma resection with a histopathologic diagnosis of adrenal cortical adenoma. After surgery, the HT of this patient was immediately reversed, and the concentration of serum potassium went back to normal. Then, this patient was administered with replacement therapy of insulin and levothyroxine sodium tablets (L-T4).
UNASSIGNED: Primary aldosteronism (PA) is a common cause of secondary hypertension originating from hormones. Type 3 autoimmune polyendocrine syndrome (APS-3) is characterized by the simultaneous or subsequent occurrence of autoimmune-mediated endocrine gland damage, except for Addison disease. Here we reported an extremely rare case of a 63-year-old woman with PA and APS-3 who initially presented with hypertension (HT). The APS-3 of this patient mainly exhibited type 1 diabetes mellitus (T1DM) and Hashimoto\'s thyroiditis. She underwent the adrenal adenoma resection with a histopathologic diagnosis of adrenal cortical adenoma. After surgery, the HT of this patient was immediately reversed, and the concentration of serum potassium went back to normal. Then, this patient was administered with replacement therapy of insulin and levothyroxine sodium tablets (L-T4).
摘要：
■原发性醛固酮增多症伴3型自身免疫性多内分泌综合征是一种罕见的高内分泌和低内分泌腺体功能的组合。包括手术和替代疗法在内的综合治疗可能是一种有效的策略。
■原发性醛固酮增多症（PA）是源于激素的继发性高血压的常见原因。3型自身免疫性多内分泌综合征（APS-3）的特征是同时或随后发生自身免疫介导的内分泌腺损害，除了艾迪生病.在这里，我们报告了一例极为罕见的病例，即一名63岁的PA和APS-3患者最初患有高血压（HT）。该患者的APS-3主要表现为1型糖尿病（T1DM）和桥本甲状腺炎。她接受了肾上腺腺瘤切除术，组织病理学诊断为肾上腺皮质腺瘤。手术后,该患者的HT立即逆转，血清钾浓度恢复正常。然后，该患者接受胰岛素和左甲状腺素钠片(L-T4)替代治疗.
■原发性醛固酮增多症（PA）是源于激素的继发性高血压的常见原因。3型自身免疫性多内分泌综合征（APS-3）的特征是同时或随后发生自身免疫介导的内分泌腺损害，除了艾迪生病.在这里，我们报告了一例极为罕见的病例，即一名63岁的PA和APS-3患者最初患有高血压（HT）。该患者的APS-3主要表现为1型糖尿病（T1DM）和桥本甲状腺炎。她接受了肾上腺腺瘤切除术，组织病理学诊断为肾上腺皮质腺瘤。手术后,该患者的HT立即逆转，血清钾浓度恢复正常。然后，该患者接受胰岛素和左甲状腺素钠片(L-T4)替代治疗.
