Abstract：
UNASSIGNED: The optimal length of epidural use following open pancreaticoduodenectomy has not been defined. The aim of this study was to investigate whether the length of patient-controlled epidural analgesia affected pain and ability to mobilise on epidural termination following open pancreaticoduodenectomy in the context of enhanced recovery after surgery.
UNASSIGNED: A retrospective single-centre cohort analysis was performed between November 2015 and December 2021 on patients who underwent open pancreaticoduodenectomy. As part of a continual review process of the enhanced recovery after surgery protocol, patient-controlled epidural analgesia duration changed allowing stratification of patients into either three- or five-day patient-controlled epidural analgesia groups.
UNASSIGNED: Of the 196 patients identified, 157 were included with 80 (50.9%) and 77 (49.1%) allocated to the three-day and five-day patient-controlled epidural analgesia groups, respectively. Patient-controlled epidural analgesia termination on postoperative day 3 was associated with transiently higher pain and less mobilisation, although no greater rescue analgesia requirement. Conversely, longer patient-controlled epidural analgesia usage following open pancreaticoduodenectomy was associated with less pain and greater mobilisation in the immediate postoperative period.
UNASSIGNED: Earlier patient-controlled epidural analgesia termination transiently leads to increased pain and decreased mobilisation following open pancreaticoduodenectomy. Ensuring appropriate analgesia requirements or longer patient-controlled epidural analgesia usage should be considered to avoid patient discomfort and enhance recovery.
UNASSIGNED: A retrospective single-centre cohort analysis was performed between November 2015 and December 2021 on patients who underwent open pancreaticoduodenectomy. As part of a continual review process of the enhanced recovery after surgery protocol, patient-controlled epidural analgesia duration changed allowing stratification of patients into either three- or five-day patient-controlled epidural analgesia groups.
UNASSIGNED: Of the 196 patients identified, 157 were included with 80 (50.9%) and 77 (49.1%) allocated to the three-day and five-day patient-controlled epidural analgesia groups, respectively. Patient-controlled epidural analgesia termination on postoperative day 3 was associated with transiently higher pain and less mobilisation, although no greater rescue analgesia requirement. Conversely, longer patient-controlled epidural analgesia usage following open pancreaticoduodenectomy was associated with less pain and greater mobilisation in the immediate postoperative period.
UNASSIGNED: Earlier patient-controlled epidural analgesia termination transiently leads to increased pain and decreased mobilisation following open pancreaticoduodenectomy. Ensuring appropriate analgesia requirements or longer patient-controlled epidural analgesia usage should be considered to avoid patient discomfort and enhance recovery.
摘要：
■开放胰十二指肠切除术后硬膜外使用的最佳时间尚未确定。这项研究的目的是调查患者自控硬膜外镇痛的时间长短是否会影响开放式胰十二指肠切除术后硬膜外终止时的疼痛和动员能力。
在2015年11月至2021年12月期间对接受开放式胰十二指肠切除术的患者进行了回顾性单中心队列分析。作为手术后增强恢复方案的持续审查过程的一部分，患者自控硬膜外镇痛持续时间改变,允许将患者分为3天或5天患者自控硬膜外镇痛组.
■在确定的196名患者中，纳入157例，其中80例（50.9%）和77例（49.1%）分配给3天和5天患者自控硬膜外镇痛组，分别。术后第3天终止患者自控硬膜外镇痛与短暂较高的疼痛和较少的动员有关，虽然没有更大的抢救镇痛要求。相反，开腹胰十二指肠切除术后患者自控硬膜外镇痛的使用时间较长,与术后即刻疼痛减轻和活动增强相关.
■早期患者自控硬膜外镇痛终止会导致开放胰十二指肠切除术后疼痛增加和活动减少。应考虑确保适当的镇痛要求或更长的患者自控硬膜外镇痛使用，以避免患者不适并促进康复。
在2015年11月至2021年12月期间对接受开放式胰十二指肠切除术的患者进行了回顾性单中心队列分析。作为手术后增强恢复方案的持续审查过程的一部分，患者自控硬膜外镇痛持续时间改变,允许将患者分为3天或5天患者自控硬膜外镇痛组.
■在确定的196名患者中，纳入157例，其中80例（50.9%）和77例（49.1%）分配给3天和5天患者自控硬膜外镇痛组，分别。术后第3天终止患者自控硬膜外镇痛与短暂较高的疼痛和较少的动员有关，虽然没有更大的抢救镇痛要求。相反，开腹胰十二指肠切除术后患者自控硬膜外镇痛的使用时间较长,与术后即刻疼痛减轻和活动增强相关.
■早期患者自控硬膜外镇痛终止会导致开放胰十二指肠切除术后疼痛增加和活动减少。应考虑确保适当的镇痛要求或更长的患者自控硬膜外镇痛使用，以避免患者不适并促进康复。
