METHODS: This sample was N = 2950 pediatric patients with BPD (ages 10-19) across the U.S. Data came from the NeuroBlu database, which includes data from 30 U.S. healthcare systems and hundreds of hospitals. Poisson regressions and chi-squared tests determined whether gender, race, and ethnicity were associated with (1) number of unique psychiatric medications prescribed and (2) number of unique medication classes prescribed.
RESULTS: Roughly two-thirds (64.85%) of youth were prescribed any medications. Of these youth, 79.40% were prescribed ≥ 2 unique medications and 72.66% were prescribed ≥ 2 unique medications classes. The mean number of unique medications was 3.50 (SD = 2.50). The mean number of unique medication classes was 2.35 (SD = 1.15). The most commonly prescribed medication classes were antidepressants and antipsychotics, which were often prescribed in combination. Poisson regressions showed that boys were prescribed more unique medications (M = 3.67) than girls (M = 3.47). Non-Latinx youth were prescribed significantly more unique medications (M = 44.12) than Latinx youth (M = 3.60, p = .01).
CONCLUSIONS: Results characterize psychiatric medication prescribing practices in youth with BPD. Prescribing practices vary by demographics, such that boys and non-Latinx youth are prescribed more medications than girls and Latinx youth, respectively. These demographic differences suggest that prescribers may treat BPD differently based on patient demographic characteristics.
方法:该样本是美国N=2950名患有BPD的儿科患者(10-19岁),数据来自NeuroBlu数据库,其中包括来自30个美国医疗保健系统和数百家医院的数据。泊松回归和卡方检验确定性别,种族,和种族与(1)处方的独特精神病药物的数量和(2)处方的独特药物类别的数量相关。
结果:大约三分之二(64.85%)的年轻人服用了任何药物。在这些年轻人中,79.40%的处方≥2种独特药物,72.66%的处方≥2种独特药物类别。独特药物的平均数量为3.50(SD=2.50)。独特药物类别的平均数量为2.35(SD=1.15)。最常见的处方药是抗抑郁药和抗精神病药,这通常是组合开的。泊松回归显示,男孩比女孩(M=3.47)服用更多的独特药物(M=3.67)。非拉丁裔青年处方的独特药物(M=44.12)明显多于拉丁裔青年(M=3.60,p=0.01)。
结论:结果描述了患有BPD的年轻人的精神病药物处方实践。处方实践因人口统计学而异,这样男孩和非拉丁裔青年比女孩和拉丁裔青年服用更多的药物,分别。这些人口统计学差异表明,处方者可能会根据患者的人口统计学特征对BPD进行不同的治疗。