Abstract：
BACKGROUND: Osteoporotic vertebral compression fracture (OVCF) is a common consequence of osteoporosis and can significantly impact the quality of life for affected individuals. Despite treatment options such as vertebroplasty and kyphoplasty, many patients continue to experience residual back pain (RBP) even after the fracture has healed. The incidence of RBP after OVCF treatment varies among studies, and there is a need for further research to understand the risk factors associated with RBP.
METHODS: A systematic review and meta-analysis were conducted following the PRISMA guidelines. Electronic databases were searched, and relevant studies were selected based on inclusion and exclusion criteria. Data extraction and quality assessment were performed independently by two authors. Statistical analysis included single-proportion meta-analyses and pooling of odds ratios (OR) using the inverse-variance method, to calculate the overall incidences of RBP and cement leakage and identify risk factors associated with RBP.
RESULTS: A total of 19 studies were included in the analysis. The overall incidences of RBP and cement leakage were found to be 16% and 18%, respectively. Several risk factors were identified, including gender, bone mineral density, depression, baseline visual analog scale (VAS) score, intravertebral vacuum cleft, number of fractured segments, cement distribution, history of vertebral fracture, thoracolumbar fascial injury, and fracture non-union.
CONCLUSIONS: This study provides potential value within the scope of the incidence and risk factors of RBP following treatment of OVCFs. The identified risk factors can help clinicians identify high-risk patients and tailor appropriate interventions. Future research should focus on standardizing the definition of RBP and patient selection criteria to improve the accuracy of estimates and facilitate better management strategies for OVCF patients.
METHODS: A systematic review and meta-analysis were conducted following the PRISMA guidelines. Electronic databases were searched, and relevant studies were selected based on inclusion and exclusion criteria. Data extraction and quality assessment were performed independently by two authors. Statistical analysis included single-proportion meta-analyses and pooling of odds ratios (OR) using the inverse-variance method, to calculate the overall incidences of RBP and cement leakage and identify risk factors associated with RBP.
RESULTS: A total of 19 studies were included in the analysis. The overall incidences of RBP and cement leakage were found to be 16% and 18%, respectively. Several risk factors were identified, including gender, bone mineral density, depression, baseline visual analog scale (VAS) score, intravertebral vacuum cleft, number of fractured segments, cement distribution, history of vertebral fracture, thoracolumbar fascial injury, and fracture non-union.
CONCLUSIONS: This study provides potential value within the scope of the incidence and risk factors of RBP following treatment of OVCFs. The identified risk factors can help clinicians identify high-risk patients and tailor appropriate interventions. Future research should focus on standardizing the definition of RBP and patient selection criteria to improve the accuracy of estimates and facilitate better management strategies for OVCF patients.
摘要：
背景：骨质疏松性椎体压缩性骨折（OVCF）是骨质疏松症的常见后果，可以显着影响患者的生活质量。尽管有椎体成形术和椎体后凸成形术等治疗选择，即使骨折愈合后，许多患者仍继续经历残余背痛（RBP）。OVCF治疗后RBP的发生率因研究而异，需要进一步研究以了解与RBP相关的危险因素。
方法：按照PRISMA指南进行系统评价和荟萃分析。搜索了电子数据库，并根据纳入和排除标准选择相关研究.数据提取和质量评估由两名作者独立进行。统计分析包括单比例荟萃分析和使用逆方差方法的比值比（OR）汇集，计算RBP和水泥渗漏的总体发生率，并确定与RBP相关的危险因素。
结果：共19项研究纳入分析。发现RBP和水泥渗漏的总发生率为16%和18%，分别。确定了几个风险因素，包括性别,骨矿物质密度，抑郁症,基线视觉模拟量表(VAS)评分，椎内真空裂隙，断裂段的数量，水泥分布，椎骨骨折史,胸腰椎筋膜损伤，骨折不愈合。
结论：本研究在OVCFs治疗后RBP的发生率和危险因素范围内提供了潜在价值。确定的风险因素可以帮助临床医生识别高风险患者并制定适当的干预措施。未来的研究应集中于规范RBP的定义和患者选择标准，以提高估计的准确性并促进OVCF患者更好的管理策略。
方法：按照PRISMA指南进行系统评价和荟萃分析。搜索了电子数据库，并根据纳入和排除标准选择相关研究.数据提取和质量评估由两名作者独立进行。统计分析包括单比例荟萃分析和使用逆方差方法的比值比（OR）汇集，计算RBP和水泥渗漏的总体发生率，并确定与RBP相关的危险因素。
结果：共19项研究纳入分析。发现RBP和水泥渗漏的总发生率为16%和18%，分别。确定了几个风险因素，包括性别,骨矿物质密度，抑郁症,基线视觉模拟量表(VAS)评分，椎内真空裂隙，断裂段的数量，水泥分布，椎骨骨折史,胸腰椎筋膜损伤，骨折不愈合。
结论：本研究在OVCFs治疗后RBP的发生率和危险因素范围内提供了潜在价值。确定的风险因素可以帮助临床医生识别高风险患者并制定适当的干预措施。未来的研究应集中于规范RBP的定义和患者选择标准，以提高估计的准确性并促进OVCF患者更好的管理策略。
