PD - L1 稳定性的 p16 依赖性增加调节衰老细胞的免疫监视。
Mesh : Cellular Senescence / immunology B7-H1 Antigen / metabolism genetics Cyclin-Dependent Kinase Inhibitor p16 / metabolism genetics Animals Humans Protein Stability Cyclin-Dependent Kinase 4 / metabolism genetics Immunologic Surveillance Mice, Inbred C57BL Cyclin-Dependent Kinase 6 / metabolism genetics Mice Proteolysis Receptors, IgG / metabolism Inflammation / immunology metabolism pathology genetics
来 源:
DOI:10.1038/s41556-024-01465-0
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