Abstract：
Oxygen-generating biomaterials are emerging as a groundbreaking solution for transforming cardiovascular engineering. These biomaterials generate and release oxygen within various biomedical applications, marking a new frontier in healthcare. Most cardiovascular treatments face a significant challenge, ensuring a consistent oxygen supply to nurture engineered tissues or even implanted devices. Traditional methods relying on passive oxygen diffusion often fall short, hindering functional cardiovascular tissue development. Oxygen-generating biomaterials, incorporating agents like calcium peroxide, provide a controlled oxygen source to the surrounding cells. This innovation potentially enhances cell viability, stimulates growth and boosts metabolic activity crucial for tissue health. Applications include repairing cardiac and vascular tissues, disease modeling, drug testing and personalized medicine, promising tailored treatments. Challenges like material toxicity and oxygen release control need consideration. As research progresses, the use of these innovative biomaterials in clinical translation could reshape cardiovascular healthcare, revolutionizing patient outcomes in heart disease treatment.
摘要：
产生氧气的生物材料正在成为转变心血管工程的开创性解决方案。这些生物材料在各种生物医学应用中产生和释放氧气，标志着医疗保健的新前沿。大多数心血管治疗面临重大挑战，确保一致的氧气供应培育工程组织或甚至植入装置。传统的依靠被动氧扩散的方法往往不够,阻碍功能性心血管组织发育。产氧生物材料,掺入诸如过氧化钙之类的试剂，向周围细胞提供受控的氧气源。这项创新有可能增强细胞活力，刺激生长并促进对组织健康至关重要的代谢活动。应用包括修复心脏和血管组织，疾病建模,药物测试和个性化医疗，有前途的定制治疗。需要考虑材料毒性和氧气释放控制等挑战。随着研究的进展,在临床转化中使用这些创新的生物材料可以重塑心血管医疗保健，彻底改变了心脏病治疗的患者结果。
