关键词: Biopsy Medical devices Phantoms Radiology Rapid prototyping

来  源:   DOI:10.1186/s41205-024-00227-w   PDF(Pubmed)

Abstract:
BACKGROUND: 3D printers have gained prominence in rapid prototyping and viable in creating dimensionally accurate objects that are both safe within a Magnetic Resonance Imaging (MRI) environment and visible in MRI scans. A challenge when making MRI-visible objects using 3D printing is that hard plastics are invisible in standard MRI scans, while fluids are not. So typically, a hollow object will be printed and filled with a liquid that will be visible in MRI scans. This poses an engineering challenge however since objects created using traditional Fused Deposition Modeling (FDM) 3D-printing techniques are prone to leakage. Digital Light Processing (DLP) is a relatively modern and affordable 3D-printing technique using UV-hardened resin, capable of creating objects that are inherently liquid-tight. When printing hollow parts using DLP printers, one typically requires adding drainage holes for uncured liquid resin to escape during the printing process. If this is not done liquid resin will remain inside the object, which in our application is the desired outcome.
OBJECTIVE: We devised a method to produce an inherently MRI-visible accessory using DLP technology with low dimensional tolerance to facilitate MRI-guided breast biopsies.
METHODS: By hollowing out the object without adding drainage holes and tuning printing parameters such as z-lift distance to retain as much uncured liquid resin inside as possible through surface tension, objects that are inherently visible in MRI scans can be created without further post-processing treatment.
RESULTS: Objects created through our method are simple and inexpensive to recreate, have minimal manufacturing steps, and are shown to be dimensionally exact and inherently MRI visible to be directly used in various applications without further treatment.
CONCLUSIONS: Our proposed method of manufacturing objects that are inherently both MRI safe, and MRI visible. The proposed process is simple and does not require additional materials and tools beyond a DLP 3D-printer. With only an inexpensive DLP 3D-printer kit and basic cleaning and sanitation materials found in the hospital, we have demonstrated the viability of our process by successfully creating an object containing fine structures with low spatial tolerances used for MRI-guided breast biopsies.
摘要:
背景:3D打印机在快速原型制作中获得了突出的地位,并且可以创建尺寸精确的物体,这些物体在磁共振成像(MRI)环境中既安全又在MRI扫描中可见。使用3D打印制作MRI可见物体时的一个挑战是硬塑料在标准MRI扫描中是不可见的,而液体不是。所以通常情况下,将打印中空物体并填充在MRI扫描中可见的液体。然而,这提出了工程挑战,因为使用传统的熔融沉积建模(FDM)3D打印技术创建的对象容易泄漏。数字光处理(DLP)是一种使用紫外线硬化树脂的相对现代且经济实惠的3D打印技术,能够创造出固有的液体密封的物体。使用DLP打印机打印空心零件时,通常需要添加排水孔以使未固化的液体树脂在打印过程中逸出。如果不这样做,液体树脂将留在物体内部,在我们的应用中是期望的结果。
目的:我们设计了一种使用DLP技术制造固有的MRI可见附件的方法,该附件具有低尺寸公差,以促进MRI引导的乳腺活检。
方法:通过在不增加排水孔的情况下将物体挖空,并调整z提升距离等印刷参数,以通过表面张力在内部保留尽可能多的未固化液体树脂,可以创建在MRI扫描中固有可见的对象,而无需进一步的后处理处理。
结果:通过我们的方法创建的对象是简单且廉价的重新创建,有最少的制造步骤,并且显示出尺寸精确且固有的MRI可见,无需进一步治疗即可直接用于各种应用。
结论:我们提出的制造物体的方法本质上既是MRI安全的,MRI可见。拟议的过程很简单,不需要DLP3D打印机以外的其他材料和工具。只有便宜的DLP3D打印机套件和基本的清洁和卫生材料在医院找到,我们已经通过成功创建一个包含空间容差低的精细结构的物体来证明我们的方法的可行性,该物体用于MRI引导的乳腺活检.
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