Abstract：
BACKGROUND: Temporal concavities result from reduced subcutaneous fat and bone structure variations, impacting facial aesthetics. Filling treatments, including autologous fat grafts, synthetic fillers, and biological materials, are used for enhancement. Autologous fat grafting is promising but limited by unpredictable fat absorption and nonstandardized procedures. This study aims to assess the clinical effectiveness of mechanical micronized fat in combination with autologous granular fat grafting for lipofilling in the correction of temporal deformities.
METHODS: Patients (n = 37, mean age = 37.48) with temporal concavity caused by aging and Inherently inadequate capacity were enrolled and divided into control group (n = 10) and study group (n = 9) according to different fat grafts. Control group received pure autologous granular fat, with an average volume of approximately 19.30 mL. In contrast, the study group used mechanical micronized fat along with autologous granular fat co-injection through an 18G needle with an average injection volume of about 18.89 mL. All autologous fat collected from patients\' abdominal and thighs. Information, including postoperative clinical efficacy scored by various plastic surgeons for the comparison of preoperative and postoperative photos of patients, patient satisfaction, and complications between the two groups, was documented. Additionally, changes in patients\' quality of life were evaluated using the FACE-Q scale.
RESULTS: Six months after surgery, the efficacy of temporal filling in the study group (6.69 ± 0.64) was higher than the control group (6.37 ± 0.67) (P = 0.0048). The patient satisfaction was more prominent in the study group (6.28 ± 0.87) than in the control group (5.80 ± 0.71) (P = 0.0449). Differences between above two observation indicators were statistically significant (P < 0.05). The FACE-Q scale items, which assess psychological health, social functioning, and early life impact, showed higher scores in the study group both before the surgery (psychological health: 59.22 ± 3.53, social functioning: 64.75 ± 3.15) and 6 months after the surgery (psychological health: 69.44 ± 4.50, social functioning: 75.33 ± 3.81, early life impact: 74.21 ± 0.70) (P > 0.05). Notably, only one micronodule formation was detected among all patients.
CONCLUSIONS: Mechanical micronized fat combined with autologous granular fat improve the clinical effect of treating concavity in temporal region, which is worthy of further promotion and application.
METHODS: Patients (n = 37, mean age = 37.48) with temporal concavity caused by aging and Inherently inadequate capacity were enrolled and divided into control group (n = 10) and study group (n = 9) according to different fat grafts. Control group received pure autologous granular fat, with an average volume of approximately 19.30 mL. In contrast, the study group used mechanical micronized fat along with autologous granular fat co-injection through an 18G needle with an average injection volume of about 18.89 mL. All autologous fat collected from patients\' abdominal and thighs. Information, including postoperative clinical efficacy scored by various plastic surgeons for the comparison of preoperative and postoperative photos of patients, patient satisfaction, and complications between the two groups, was documented. Additionally, changes in patients\' quality of life were evaluated using the FACE-Q scale.
RESULTS: Six months after surgery, the efficacy of temporal filling in the study group (6.69 ± 0.64) was higher than the control group (6.37 ± 0.67) (P = 0.0048). The patient satisfaction was more prominent in the study group (6.28 ± 0.87) than in the control group (5.80 ± 0.71) (P = 0.0449). Differences between above two observation indicators were statistically significant (P < 0.05). The FACE-Q scale items, which assess psychological health, social functioning, and early life impact, showed higher scores in the study group both before the surgery (psychological health: 59.22 ± 3.53, social functioning: 64.75 ± 3.15) and 6 months after the surgery (psychological health: 69.44 ± 4.50, social functioning: 75.33 ± 3.81, early life impact: 74.21 ± 0.70) (P > 0.05). Notably, only one micronodule formation was detected among all patients.
CONCLUSIONS: Mechanical micronized fat combined with autologous granular fat improve the clinical effect of treating concavity in temporal region, which is worthy of further promotion and application.
摘要：
背景：颞骨凹陷是由皮下脂肪减少和骨骼结构变化引起的，影响面部美学。充填处理,包括自体脂肪移植,合成填料,和生物材料，用于增强。自体脂肪移植是有希望的，但受到不可预测的脂肪吸收和非标准化程序的限制。本研究旨在评估机械微粉化脂肪与自体颗粒脂肪移植结合用于脂质填充的临床有效性。
方法：纳入年龄增长所致颞部凹陷和固有容量不足的患者（n=37，平均年龄=37.48），根据脂肪移植的不同分为对照组（n=10）和研究组（n=9）。对照组接受单纯的自体颗粒脂肪，平均体积约为19.30mL。相比之下,研究组使用机械微粉化脂肪和自体颗粒脂肪通过18G针头共注射,平均注射量约为18.89mL.从患者腹部和大腿收集的所有自体脂肪。信息，包括各种整形外科医生对患者术前和术后照片进行比较的术后临床疗效评分，患者满意度,两组之间的并发症，被记录在案。此外,使用FACE-Q量表评估患者生活质量的变化。
结果：手术后六个月，研究组的时间填充疗效（6.69±0.64）高于对照组（6.37±0.67）（P=0.0048）。研究组患者满意度(6.28±0.87)高于对照组(5.80±0.71)(P=0.0449)。上述两项观察指标差异有统计学意义(P<0.05)。FACE-Q量表项目，评估心理健康，社会功能,和早期生活的影响，研究组术前(心理健康:59.22±3.53,社会功能:64.75±3.15)和术后6个月(心理健康:69.44±4.50,社会功能:75.33±3.81,早期生活影响:74.21±0.70)评分均较高(P>0.05)。值得注意的是,在所有患者中仅检测到1例微结节形成.
结论：机械微粉化脂肪联合自体颗粒脂肪可提高颞区凹陷的临床疗效。值得进一步推广应用。
方法：纳入年龄增长所致颞部凹陷和固有容量不足的患者（n=37，平均年龄=37.48），根据脂肪移植的不同分为对照组（n=10）和研究组（n=9）。对照组接受单纯的自体颗粒脂肪，平均体积约为19.30mL。相比之下,研究组使用机械微粉化脂肪和自体颗粒脂肪通过18G针头共注射,平均注射量约为18.89mL.从患者腹部和大腿收集的所有自体脂肪。信息，包括各种整形外科医生对患者术前和术后照片进行比较的术后临床疗效评分，患者满意度,两组之间的并发症，被记录在案。此外,使用FACE-Q量表评估患者生活质量的变化。
结果：手术后六个月，研究组的时间填充疗效（6.69±0.64）高于对照组（6.37±0.67）（P=0.0048）。研究组患者满意度(6.28±0.87)高于对照组(5.80±0.71)(P=0.0449)。上述两项观察指标差异有统计学意义(P<0.05)。FACE-Q量表项目，评估心理健康，社会功能,和早期生活的影响，研究组术前(心理健康:59.22±3.53,社会功能:64.75±3.15)和术后6个月(心理健康:69.44±4.50,社会功能:75.33±3.81,早期生活影响:74.21±0.70)评分均较高(P>0.05)。值得注意的是,在所有患者中仅检测到1例微结节形成.
结论：机械微粉化脂肪联合自体颗粒脂肪可提高颞区凹陷的临床疗效。值得进一步推广应用。
