Abstract：
OBJECTIVE: To investigate the influence of different denture-bearing conditions on the masticatory function and patient-reported outcome measures (PROMs) of complete denture wearers.
METHODS: Sixty edentulous patients were selected and allocated into two groups according to the American College of Prosthodontics\' (ACP) classification: non-atrophic (NAT) (Classes I and II) (n = 24) and atrophic (AT) (Classes III and IV) (n = 36). All patients received new complete dentures (CDs). The objective variables (masticatory performance and swallowing threshold) were assessed as well as the PROMs (oral health-related quality of life (OHIP-EDENT), patient satisfaction) and quality of the prosthesis, at baseline (using the old CD) and after 4 months new prostheses use. Data were analyzed by Mann-Whitney test followed by the Generalized Equations Estimation (GEE), linear regression and Chi-square test.
RESULTS: Higher masticatory performance was observed in the NAT group (p < .05) for both time points, baseline and after 4 months. However, compared to baseline, both groups showed significant masticatory improvement after 4 months (p < .05). Satisfaction and overall quality of life improved after 4 months with no difference between groups (p > .05). Regarding the quality of the CD, baseline results were significantly (p < .05) lower in the AT group, but after 4 months, no significant differences were found between groups and in intragroup analysis (p > .05).
CONCLUSIONS: The denture-bearing conditions seems to impact masticatory function, but the PROMs are barely affected.
METHODS: Sixty edentulous patients were selected and allocated into two groups according to the American College of Prosthodontics\' (ACP) classification: non-atrophic (NAT) (Classes I and II) (n = 24) and atrophic (AT) (Classes III and IV) (n = 36). All patients received new complete dentures (CDs). The objective variables (masticatory performance and swallowing threshold) were assessed as well as the PROMs (oral health-related quality of life (OHIP-EDENT), patient satisfaction) and quality of the prosthesis, at baseline (using the old CD) and after 4 months new prostheses use. Data were analyzed by Mann-Whitney test followed by the Generalized Equations Estimation (GEE), linear regression and Chi-square test.
RESULTS: Higher masticatory performance was observed in the NAT group (p < .05) for both time points, baseline and after 4 months. However, compared to baseline, both groups showed significant masticatory improvement after 4 months (p < .05). Satisfaction and overall quality of life improved after 4 months with no difference between groups (p > .05). Regarding the quality of the CD, baseline results were significantly (p < .05) lower in the AT group, but after 4 months, no significant differences were found between groups and in intragroup analysis (p > .05).
CONCLUSIONS: The denture-bearing conditions seems to impact masticatory function, but the PROMs are barely affected.
摘要：
目的：探讨不同义齿条件对全口义齿佩戴者咀嚼功能和患者报告结局指标（PROMs）的影响。
方法：根据美国口腔修复学会（ACP）分类，选择60例无牙患者并分为两组：非萎缩性（NAT）（I类和II类）（n=24）和萎缩性（AT）（III类和IV类）（n=36）。所有患者均接受新的全口义齿（CD）。评估了客观变量（咀嚼性能和吞咽阈值）以及PROM（口腔健康相关生活质量（OHIP-EDENT），患者满意度)和假体质量，在基线（使用旧CD）和4个月后使用新的假体。数据通过Mann-Whitney检验和广义方程估计(GEE)进行分析，线性回归和卡方检验。
结果：在两个时间点的NAT组中观察到更高的咀嚼性能（p<.05），基线和4个月后。然而,与基线相比，两组患者在4个月后表现出显著的咀嚼改善(p<.05)。4个月后满意度和总体生活质量改善，组间无差异（p>0.05）。关于CD的质量，AT组的基线结果显着降低（p<0.05），但4个月后,组间和组内分析均无显著差异(p>.05)。
结论：义齿承载条件似乎影响咀嚼功能，但是PROM几乎没有受到影响。
方法：根据美国口腔修复学会（ACP）分类，选择60例无牙患者并分为两组：非萎缩性（NAT）（I类和II类）（n=24）和萎缩性（AT）（III类和IV类）（n=36）。所有患者均接受新的全口义齿（CD）。评估了客观变量（咀嚼性能和吞咽阈值）以及PROM（口腔健康相关生活质量（OHIP-EDENT），患者满意度)和假体质量，在基线（使用旧CD）和4个月后使用新的假体。数据通过Mann-Whitney检验和广义方程估计(GEE)进行分析，线性回归和卡方检验。
结果：在两个时间点的NAT组中观察到更高的咀嚼性能（p<.05），基线和4个月后。然而,与基线相比，两组患者在4个月后表现出显著的咀嚼改善(p<.05)。4个月后满意度和总体生活质量改善，组间无差异（p>0.05）。关于CD的质量，AT组的基线结果显着降低（p<0.05），但4个月后,组间和组内分析均无显著差异(p>.05)。
结论：义齿承载条件似乎影响咀嚼功能，但是PROM几乎没有受到影响。
