Abstract：
BACKGROUND: Over the past decade, the production and consumption of organic food (OF) have received increasing interest. Scientific studies have shown better quality of organic fruit and vegetables (FV) in terms of nutrients and pesticide contents, but it appears difficult to conclude if there are potentially greater health benefits of these products compared with conventional food (CF).
OBJECTIVE: To determine whether the current scientific literature demonstrates that a diet rich in organic FV is healthier than 1 based on conventional produce.
METHODS: A systematic search was conducted using the PubMed and Web of Science databases for articles published between January 2003 and December 2022. Articles were analyzed uniformly by 2 reviewer, using a specific template summary sheet, and scored from 1 to 5. The level of evidence and the quality of studies in humans were assessed using the Jadad score and the French National Authority for Health method.
RESULTS: A total of 12 human studies were included. Studies often reported contradictory or even opposite results, with methodological limitations. Only 6 of the 12 studies found significant associations between OF and the health outcomes evaluated.
CONCLUSIONS: The current data do not enable a firm conclusion about a greater health benefit for a diet rich in FV based on products grown organically compared with conventional farming. There is a paucity of available data and considerable heterogeneity in study designs (participants, exposures, durations, health outcomes, and residual confounding factors). Well-designed interventional studies are required.
OBJECTIVE: To determine whether the current scientific literature demonstrates that a diet rich in organic FV is healthier than 1 based on conventional produce.
METHODS: A systematic search was conducted using the PubMed and Web of Science databases for articles published between January 2003 and December 2022. Articles were analyzed uniformly by 2 reviewer, using a specific template summary sheet, and scored from 1 to 5. The level of evidence and the quality of studies in humans were assessed using the Jadad score and the French National Authority for Health method.
RESULTS: A total of 12 human studies were included. Studies often reported contradictory or even opposite results, with methodological limitations. Only 6 of the 12 studies found significant associations between OF and the health outcomes evaluated.
CONCLUSIONS: The current data do not enable a firm conclusion about a greater health benefit for a diet rich in FV based on products grown organically compared with conventional farming. There is a paucity of available data and considerable heterogeneity in study designs (participants, exposures, durations, health outcomes, and residual confounding factors). Well-designed interventional studies are required.
摘要：
背景：在过去的十年中，有机食品（OF）的生产和消费受到越来越多的关注。科学研究表明，就营养素和农药含量而言，有机水果和蔬菜（FV）的质量更高，但与传统食品（CF）相比，这些产品是否有潜在更大的健康益处似乎很难得出结论。
目的：确定当前的科学文献是否表明富含有机FV的饮食比常规产品的饮食更健康。
方法：使用PubMed和WebofScience数据库对2003年1月至2022年12月之间发表的文章进行了系统搜索。文章由2名审稿人统一分析，使用特定的模板汇总表，得分从1到5。使用Jadad评分和法国国家卫生管理局方法评估了人类的证据水平和研究质量。
结果：共纳入12项人体研究。研究经常报告矛盾甚至相反的结果，有方法论上的局限性。12项研究中只有6项发现OF与评估的健康结果之间存在显着关联。
结论：目前的数据无法得出关于与传统农业相比，有机种植的产品富含FV的饮食具有更大的健康益处的确切结论。研究设计中缺乏可用数据和相当大的异质性(参与者，暴露,持续时间,健康结果，和残余混杂因素)。需要精心设计的介入研究。
目的：确定当前的科学文献是否表明富含有机FV的饮食比常规产品的饮食更健康。
方法：使用PubMed和WebofScience数据库对2003年1月至2022年12月之间发表的文章进行了系统搜索。文章由2名审稿人统一分析，使用特定的模板汇总表，得分从1到5。使用Jadad评分和法国国家卫生管理局方法评估了人类的证据水平和研究质量。
结果：共纳入12项人体研究。研究经常报告矛盾甚至相反的结果，有方法论上的局限性。12项研究中只有6项发现OF与评估的健康结果之间存在显着关联。
结论：目前的数据无法得出关于与传统农业相比，有机种植的产品富含FV的饮食具有更大的健康益处的确切结论。研究设计中缺乏可用数据和相当大的异质性(参与者，暴露,持续时间,健康结果，和残余混杂因素)。需要精心设计的介入研究。
