PDF(Pubmed)
Abstract：
UNASSIGNED: The advent and increased use of high-resolution ultrasonography has resulted in improved detection of thyroid nodules. Even with the use of various Thyroid Imaging-Reporting and Data System, accurate imaging diagnosis of malignant thyroid nodules has been suboptimal, which necessitated use of newer modalities like contrast-enhanced ultrasonography alone and in combination for this purpose. Although the combined use of various Thyroid Imaging-Reporting and Data System and contrast-enhanced ultrasonography has turned out to be accurate in many studies, the ideal way to integrate contrast-enhanced ultrasonography into the Thyroid Imaging-Reporting and Data System algorithm is under-investigated.
UNASSIGNED: To estimate and compare the diagnostic accuracy of American College of Radiology Thyroid Imaging-Reporting and Data System and contrast-enhanced ultrasonography in differentiating benign and malignant nodules alone and in combination. To estimate the diagnostic accuracy of contrast-enhanced ultrasonography in re-categorisation of Thyroid Imaging-Reporting and Data System 3 and Thyroid Imaging-Reporting and Data System 4 thyroid nodules.
UNASSIGNED: This was a prospective cohort study performed in a tertiary care university-based hospital for 3 years. Adult patients with clinical or previous sonographic diagnosis of thyroid nodules were selected. Each of the nodules were assessed using ultrasonography and categorised using American College of Radiology Thyroid Imaging-Reporting and Data System criteria. The lesion was then assessed for contrast-enhanced ultrasonography features. The final diagnosis of the nodules was made using fine needle aspiration cytology. The diagnostic accuracy in diagnosis of malignant thyroid nodules for each of the American College of Radiology Thyroid Imaging-Reporting and Data System and contrast-enhanced ultrasonography alone and in combination was assessed. The diagnostic accuracy of contrast-enhanced ultrasonography in diagnosis of malignant thyroid nodules categorised as Thyroid Imaging-Reporting and Data System 3 and Thyroid Imaging-Reporting and Data System 4 was also assessed.
UNASSIGNED: American College of Radiology Thyroid Imaging-Reporting and Data System had a sensitivity, specificity, negative predictive value, positive predictive value and diagnostic accuracy of 86.6%, 54.5%, 17.4%, 97.3% and 57.7%, respectively, in diagnosis of malignant thyroid nodules. Contrast-enhanced ultrasonography had a sensitivity, specificity, negative predictive value, positive predictive value and diagnostic accuracy of 86.6%, 95.4%, 67.9%, 98.4% and 94.4%, respectively, in diagnosis of malignant thyroid nodules. Contrast-enhanced ultrasonography had sensitivity, specificity, negative predictive value, positive predictive value and diagnostic accuracy of 93.3%, 100.0%, 100.0%, 99.2% and 99.3%, respectively, in re-categorisation of Thyroid Imaging-Reporting and Data System 3 and Thyroid Imaging-Reporting and Data System 4 nodules.
UNASSIGNED: Contrast-enhanced ultrasonography can play a key role in diagnosis of malignant thyroid nodules which are categorised as indeterminate on grey-scale ultrasound.
UNASSIGNED: To estimate and compare the diagnostic accuracy of American College of Radiology Thyroid Imaging-Reporting and Data System and contrast-enhanced ultrasonography in differentiating benign and malignant nodules alone and in combination. To estimate the diagnostic accuracy of contrast-enhanced ultrasonography in re-categorisation of Thyroid Imaging-Reporting and Data System 3 and Thyroid Imaging-Reporting and Data System 4 thyroid nodules.
UNASSIGNED: This was a prospective cohort study performed in a tertiary care university-based hospital for 3 years. Adult patients with clinical or previous sonographic diagnosis of thyroid nodules were selected. Each of the nodules were assessed using ultrasonography and categorised using American College of Radiology Thyroid Imaging-Reporting and Data System criteria. The lesion was then assessed for contrast-enhanced ultrasonography features. The final diagnosis of the nodules was made using fine needle aspiration cytology. The diagnostic accuracy in diagnosis of malignant thyroid nodules for each of the American College of Radiology Thyroid Imaging-Reporting and Data System and contrast-enhanced ultrasonography alone and in combination was assessed. The diagnostic accuracy of contrast-enhanced ultrasonography in diagnosis of malignant thyroid nodules categorised as Thyroid Imaging-Reporting and Data System 3 and Thyroid Imaging-Reporting and Data System 4 was also assessed.
UNASSIGNED: American College of Radiology Thyroid Imaging-Reporting and Data System had a sensitivity, specificity, negative predictive value, positive predictive value and diagnostic accuracy of 86.6%, 54.5%, 17.4%, 97.3% and 57.7%, respectively, in diagnosis of malignant thyroid nodules. Contrast-enhanced ultrasonography had a sensitivity, specificity, negative predictive value, positive predictive value and diagnostic accuracy of 86.6%, 95.4%, 67.9%, 98.4% and 94.4%, respectively, in diagnosis of malignant thyroid nodules. Contrast-enhanced ultrasonography had sensitivity, specificity, negative predictive value, positive predictive value and diagnostic accuracy of 93.3%, 100.0%, 100.0%, 99.2% and 99.3%, respectively, in re-categorisation of Thyroid Imaging-Reporting and Data System 3 and Thyroid Imaging-Reporting and Data System 4 nodules.
UNASSIGNED: Contrast-enhanced ultrasonography can play a key role in diagnosis of malignant thyroid nodules which are categorised as indeterminate on grey-scale ultrasound.
摘要：
■高分辨率超声检查的出现和使用的增加导致甲状腺结节的检测得到改善。即使使用各种甲状腺成像报告和数据系统，甲状腺恶性结节的准确影像学诊断一直不够理想，为此，必须单独使用新的模式，例如超声造影和联合使用。尽管在许多研究中，各种甲状腺成像报告和数据系统与超声造影的结合使用已证明是准确的，将超声造影整合到甲状腺成像报告和数据系统算法中的理想方法研究不足。
■评估和比较美国放射学学会甲状腺影像报告和数据系统以及超声造影在单独和联合鉴别良性和恶性结节方面的诊断准确性。评估超声造影在甲状腺成像报告和数据系统3和甲状腺成像报告和数据系统4甲状腺结节重新分类中的诊断准确性。
■这是一项前瞻性队列研究，在一家三级护理大学医院进行了3年。选择临床或既往超声诊断为甲状腺结节的成年患者。使用超声检查评估每个结节，并使用美国放射学学会甲状腺成像报告和数据系统标准进行分类。然后评估病变的超声造影特征。使用细针穿刺细胞学检查对结节进行最终诊断。评估了美国放射学学会甲状腺成像报告和数据系统以及超声造影单独和联合使用的恶性甲状腺结节的诊断准确性。还评估了超声造影在诊断分类为甲状腺成像报告和数据系统3和甲状腺成像报告和数据系统4的恶性甲状腺结节中的诊断准确性。
■美国放射学会甲状腺成像-报告和数据系统具有敏感性，特异性，负预测值，阳性预测值和诊断准确率为86.6%，54.5%,17.4%,97.3%和57.7%，分别,诊断甲状腺恶性结节。超声造影具有敏感性，特异性，负预测值，阳性预测值和诊断准确率为86.6%，95.4%,67.9%,98.4%和94.4%，分别,诊断甲状腺恶性结节。超声造影具有敏感性，特异性，负预测值，阳性预测值和诊断准确率为93.3%，100.0%,100.0%,99.2%和99.3%，分别,甲状腺成像报告和数据系统3和甲状腺成像报告和数据系统4结节的重新分类。
■超声造影对灰阶不确定的甲状腺恶性结节的诊断具有重要意义。
■评估和比较美国放射学学会甲状腺影像报告和数据系统以及超声造影在单独和联合鉴别良性和恶性结节方面的诊断准确性。评估超声造影在甲状腺成像报告和数据系统3和甲状腺成像报告和数据系统4甲状腺结节重新分类中的诊断准确性。
■这是一项前瞻性队列研究，在一家三级护理大学医院进行了3年。选择临床或既往超声诊断为甲状腺结节的成年患者。使用超声检查评估每个结节，并使用美国放射学学会甲状腺成像报告和数据系统标准进行分类。然后评估病变的超声造影特征。使用细针穿刺细胞学检查对结节进行最终诊断。评估了美国放射学学会甲状腺成像报告和数据系统以及超声造影单独和联合使用的恶性甲状腺结节的诊断准确性。还评估了超声造影在诊断分类为甲状腺成像报告和数据系统3和甲状腺成像报告和数据系统4的恶性甲状腺结节中的诊断准确性。
■美国放射学会甲状腺成像-报告和数据系统具有敏感性，特异性，负预测值，阳性预测值和诊断准确率为86.6%，54.5%,17.4%,97.3%和57.7%，分别,诊断甲状腺恶性结节。超声造影具有敏感性，特异性，负预测值，阳性预测值和诊断准确率为86.6%，95.4%,67.9%,98.4%和94.4%，分别,诊断甲状腺恶性结节。超声造影具有敏感性，特异性，负预测值，阳性预测值和诊断准确率为93.3%，100.0%,100.0%,99.2%和99.3%，分别,甲状腺成像报告和数据系统3和甲状腺成像报告和数据系统4结节的重新分类。
■超声造影对灰阶不确定的甲状腺恶性结节的诊断具有重要意义。
