与男性发生性关系的男性中巨细胞病毒的患病率和危险因素参与了暴露前预防研究。Prevalence and Risk Factors of Cytomegalovirus Among Men Having Sex With Men Enrolled in a Pre-Exposure Prophylaxis Study.-医云文献数字医云科研云海量医学决策数据服务

Abstract：

Risk factors for cytomegalovirus (CMV) acquisition in men having sex with men remain unclear. Seroprevalence, incidence, risk factors and shedding of CMV were analyzed among participants enrolled in the HIV pre-exposure prophylaxis IPERGAY-ANRS trial. Among the 417 participants tested, 382 were seropositive at baseline (prevalence of 91.6%; 95%CI[88.5-94.1]) and 10/35 seroconverted during the study (incidence of 17.1 per 100 person-years; 95%CI[8.2-31.3]). A high number of sexual partners was independently associated with CMV seroprevalence. Shedding among CMV-seroconverters was reported for 6/9 and 2/9 at the oral and anal levels, respectively. Our data supports transmission of CMV during sexual contacts.
UNASSIGNED: ClinicalTrials.gov number, NCT01473472.

摘要：

与男性发生性关系的男性中巨细胞病毒（CMV）获得的危险因素尚不清楚。血清阳性率,发病率,我们分析了HIV暴露前预防IPERGAY-ANRS试验参与者的危险因素和CMV脱落情况.在测试的417名参与者中，382例基线血清阳性（患病率91.6%；95CI[88.5-94.1]），研究期间10/35血清转化（发病率17.1/100人年；95CI[8.2-31.3]）。大量的性伴侣与CMV血清阳性率独立相关。据报道，在口腔和肛门水平上，CMV血清转换器中的脱落分别为6/9和2/9。分别。我们的数据支持性接触期间CMV的传输。
■ClinicalTrials.gov编号，NCT01473472。