PDF(Pubmed)
Abstract：
UNASSIGNED: Long COVID is an emerging global public health issue. Socially vulnerable communities in low- and-middle-income countries were severely impacted by the pandemic and are underrepresented in research. This prospective study aimed to determine the prevalence of long COVID, its impact on health, and associated risk factors in one such community in Rio de Janeiro, Brazil.
UNASSIGNED: A total of 710 individuals aged 18 and older, with confirmed SARS-CoV-2 infection at least three months prior, were enrolled between November 25, 2021, and May 5, 2022. Participants were assessed via telephone or in person using a standardized questionnaire to evaluate their perception of recovery, symptoms, quality of life, and functional status.
UNASSIGNED: Twenty percent of participants did not feel fully recovered, 22% experienced new or persistent symptoms, 26% had worsened functional status, 18% had increased dyspnoea, and 32% reported a worse quality of life. Persistent symptoms included headache, cough, fatigue, muscle pain, and shortness of breath. Dyspnoea during the acute phase was the strongest independent predictor of worsening outcomes. Females and individuals with comorbidities were more likely to report worse recovery, functioning, dyspnoea, and quality of life.
UNASSIGNED: Our findings reveal a high burden of severe and persistent physical and mental health sequelae in a socially vulnerable community following COVID-19.
UNASSIGNED: UK Foreign, Commonwealth and Development Office and Wellcome Trust Grant (222048/Z/20/Z), Fundação Oswaldo Cruz (FIOCRUZ), Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ), and the Centers for Disease Control and Prevention (CDC).
UNASSIGNED: A total of 710 individuals aged 18 and older, with confirmed SARS-CoV-2 infection at least three months prior, were enrolled between November 25, 2021, and May 5, 2022. Participants were assessed via telephone or in person using a standardized questionnaire to evaluate their perception of recovery, symptoms, quality of life, and functional status.
UNASSIGNED: Twenty percent of participants did not feel fully recovered, 22% experienced new or persistent symptoms, 26% had worsened functional status, 18% had increased dyspnoea, and 32% reported a worse quality of life. Persistent symptoms included headache, cough, fatigue, muscle pain, and shortness of breath. Dyspnoea during the acute phase was the strongest independent predictor of worsening outcomes. Females and individuals with comorbidities were more likely to report worse recovery, functioning, dyspnoea, and quality of life.
UNASSIGNED: Our findings reveal a high burden of severe and persistent physical and mental health sequelae in a socially vulnerable community following COVID-19.
UNASSIGNED: UK Foreign, Commonwealth and Development Office and Wellcome Trust Grant (222048/Z/20/Z), Fundação Oswaldo Cruz (FIOCRUZ), Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ), and the Centers for Disease Control and Prevention (CDC).
摘要：
■长COVID是一个新兴的全球公共卫生问题。低收入和中等收入国家的社会脆弱社区受到这一流行病的严重影响，在研究中代表性不足。这项前瞻性研究旨在确定长期COVID的患病率，它对健康的影响，以及里约热内卢这样一个社区的相关风险因素，巴西。
■共有710名18岁及以上的人，至少三个月前确诊SARS-CoV-2感染，在2021年11月25日至2022年5月5日期间注册。参与者通过电话或亲自使用标准化问卷进行评估，以评估他们对康复的看法，症状,生活质量,和功能状态。
■20%的参与者没有完全康复，22%出现新的或持续的症状，26%的人功能状态恶化，18%的人呼吸困难增加，32%的人报告生活质量更差。持续的症状包括头痛，咳嗽,疲劳,肌肉疼痛，呼吸急促.急性期呼吸困难是预后恶化的最强独立预测因子。女性和有合并症的人更有可能报告康复情况较差，功能,呼吸困难,和生活质量。
■我们的研究结果表明，在COVID-19之后，在一个社会脆弱的社区中，严重和持续的身心健康后遗症负担很高。
■英国外国，联邦和发展办公室和惠康信托基金(222048/Z/20/Z)，奥斯瓦尔多·克鲁兹基金会(FIOCRUZ)，里约热内卢Estado基金会（FAPERJ），和疾病控制和预防中心（CDC）。
■共有710名18岁及以上的人，至少三个月前确诊SARS-CoV-2感染，在2021年11月25日至2022年5月5日期间注册。参与者通过电话或亲自使用标准化问卷进行评估，以评估他们对康复的看法，症状,生活质量,和功能状态。
■20%的参与者没有完全康复，22%出现新的或持续的症状，26%的人功能状态恶化，18%的人呼吸困难增加，32%的人报告生活质量更差。持续的症状包括头痛，咳嗽,疲劳,肌肉疼痛，呼吸急促.急性期呼吸困难是预后恶化的最强独立预测因子。女性和有合并症的人更有可能报告康复情况较差，功能,呼吸困难,和生活质量。
■我们的研究结果表明，在COVID-19之后，在一个社会脆弱的社区中，严重和持续的身心健康后遗症负担很高。
■英国外国，联邦和发展办公室和惠康信托基金(222048/Z/20/Z)，奥斯瓦尔多·克鲁兹基金会(FIOCRUZ)，里约热内卢Estado基金会（FAPERJ），和疾病控制和预防中心（CDC）。
