Abstract:
Human visual function depends on the biological lens, a biconvex optical element formed by coordinated, synchronous generation of growth shells produced from ordered cells at the lens equator, the distal edge of the epithelium. Growth shells are comprised of straight (St) and S-shaped (SSh) lens fibers organized in highly symmetric, sinusoidal pattern which optimizes both the refractile, transparent structure and the unique microcirculation that regulates hydration and nutrition over the lifetime of an individual. The fiber cells are characterized by diversity in composition and age. All fiber cells remain interconnected in their growth shells throughout the life of the adult lens. As an optical element, cellular differentiation is constrained by the physical properties of light and its special development accounts for its characteristic symmetry, gradient of refractive index (GRIN), short range transparent order (SRO), and functional longevity. The complex sinusoidal structure is the basis for the lens microcirculation required for the establishment and maintenance of image formation.
摘要:
人类的视觉功能取决于生物晶状体,由协调形成的双凸光学元件,从透镜赤道的有序细胞产生的生长壳的同步生成,上皮的远端边缘。生长壳由高度对称的直(St)和S形(SSh)透镜纤维组成,正弦模式优化了折射,透明的结构和独特的微循环,在个体的一生中调节水合和营养。成纤维细胞的特征在于组成和年龄的多样性。在成人晶状体的整个生命周期中,所有纤维细胞都在其生长外壳中保持互连。作为一个光学元件,细胞分化受光的物理性质的限制,其特殊的发展解释了其特有的对称性,折射率梯度(GRIN),短程透明订单(SRO),和功能长寿。复杂的正弦结构是建立和维持图像形成所需的透镜微循环的基础。