PDF(Pubmed)
Abstract：
UNASSIGNED: The perimenopausal period is marked by hormonal fluctuations that trigger a complex interplay between estrogen levels and neurotransmitters\' function, contributing to increased susceptibility to depression and anxiety in women. Concurrently, hormonal changes, coupled with alterations in vaginal tissue, lead to sexual dysfunction during this transitional phase. This study aimed at evaluating the association between menopausal symptoms and sexual dysfunction among perimenopausal women and identifying the mediating effects of depression and anxiety on this association.
UNASSIGNED: Data for the present cross-sectional study were collected from participants via Arabic versions of three questionnaires; the modified Menopausal Rating Scale (MRS), the Female Sexual Functioning Index (FSFI) and the Hospital Anxiety and Depression scale (HADS).
UNASSIGNED: Our study was conducted on 149 females with age ranged from 45 to 55 years. On studying the relation between modified MRS and HADS, the menopausal symptoms were significantly high among female with high anxiety scores. Regarding the relationship between MRS and FSFI, women with anxiety and physical and mental exhaustion had significantly lower FSFI scores than women without such symptoms (19.2 [2-31.4] vs 21.7 [3.8-30.9], p = 0.04, respectively). Furthermore, there were statistically significant negative correlations between depression scores and sexual desire (r = -0.32, p < 0.001), arousal (r = -0.25, p = 0.003), and total FSFI scores (r = -0.27, p = 0.04).
UNASSIGNED: Perimenopausal women experience a confluence of challenges related to depression, anxiety, and sexual dysfunction. Understanding the interconnectedness of hormonal and psychosocial factors is essential for tailored interventions aimed at improving mental health and sexual well-being during this transitional phase.
UNASSIGNED: Data for the present cross-sectional study were collected from participants via Arabic versions of three questionnaires; the modified Menopausal Rating Scale (MRS), the Female Sexual Functioning Index (FSFI) and the Hospital Anxiety and Depression scale (HADS).
UNASSIGNED: Our study was conducted on 149 females with age ranged from 45 to 55 years. On studying the relation between modified MRS and HADS, the menopausal symptoms were significantly high among female with high anxiety scores. Regarding the relationship between MRS and FSFI, women with anxiety and physical and mental exhaustion had significantly lower FSFI scores than women without such symptoms (19.2 [2-31.4] vs 21.7 [3.8-30.9], p = 0.04, respectively). Furthermore, there were statistically significant negative correlations between depression scores and sexual desire (r = -0.32, p < 0.001), arousal (r = -0.25, p = 0.003), and total FSFI scores (r = -0.27, p = 0.04).
UNASSIGNED: Perimenopausal women experience a confluence of challenges related to depression, anxiety, and sexual dysfunction. Understanding the interconnectedness of hormonal and psychosocial factors is essential for tailored interventions aimed at improving mental health and sexual well-being during this transitional phase.
摘要：
■围绝经期的特点是荷尔蒙波动，引发雌激素水平和神经递质功能之间复杂的相互作用，增加女性对抑郁和焦虑的易感性。同时,荷尔蒙的变化,再加上阴道组织的改变，在这个过渡阶段导致性功能障碍。这项研究旨在评估围绝经期妇女的绝经症状与性功能障碍之间的关系，并确定抑郁和焦虑在这种关系中的中介作用。
■本横断面研究的数据是通过三个问卷的阿拉伯语版本从参与者那里收集的；改良的更年期评定量表（MRS），女性性功能指数(FSFI)和医院焦虑抑郁量表(HADS)。
■我们的研究对象是149名年龄在45至55岁之间的女性。在研究改良MRS与HADS的关系时，在焦虑评分较高的女性中，更年期症状明显较高。关于MRS和FSFI之间的关系，与没有此类症状的女性相比，患有焦虑和身心疲惫的女性的FSFI评分显着降低（19.2[2-31.4]vs21.7[3.8-30.9]，p分别=0.04)。此外，抑郁评分与性欲呈显著负相关(r=-0.32,p<0.001),觉醒（r=-0.25，p=0.003），和FSFI总分（r=-0.27，p=0.04）。
■围绝经期女性经历了与抑郁症相关的一系列挑战，焦虑,和性功能障碍。了解荷尔蒙和社会心理因素的相互联系对于在此过渡阶段旨在改善心理健康和性健康的量身定制的干预措施至关重要。
■本横断面研究的数据是通过三个问卷的阿拉伯语版本从参与者那里收集的；改良的更年期评定量表（MRS），女性性功能指数(FSFI)和医院焦虑抑郁量表(HADS)。
■我们的研究对象是149名年龄在45至55岁之间的女性。在研究改良MRS与HADS的关系时，在焦虑评分较高的女性中，更年期症状明显较高。关于MRS和FSFI之间的关系，与没有此类症状的女性相比，患有焦虑和身心疲惫的女性的FSFI评分显着降低（19.2[2-31.4]vs21.7[3.8-30.9]，p分别=0.04)。此外，抑郁评分与性欲呈显著负相关(r=-0.32,p<0.001),觉醒（r=-0.25，p=0.003），和FSFI总分（r=-0.27，p=0.04）。
■围绝经期女性经历了与抑郁症相关的一系列挑战，焦虑,和性功能障碍。了解荷尔蒙和社会心理因素的相互联系对于在此过渡阶段旨在改善心理健康和性健康的量身定制的干预措施至关重要。
