PDF(Pubmed)
Abstract：
Background Hypertensive emergencies represent high-cardiovascular-risk situations defined by severe increases in blood pressure. The prevalence of hypertension in non-ST elevation myocardial infarction (NSTEMI) is higher compared to STEMI and there is a lack of studies on NSTEMI patients with hypertensive emergencies. Patients with diabetes exhibited a higher rate of hypertensive emergencies. This study\'s primary aim was to investigate the coronary artery disease profile in hypertensive emergency patients with NSTEMI, and the secondary aim was to determine the impact of diabetes on the development of hypertensive emergencies. Methodology A total of 100 patients with NSTEMI and hypertensive emergency presenting to the hospital were enrolled in the study. The duration of the study was 24 months. The patients were also sub-grouped into diabetic and nondiabetic. Baseline characteristics were noted, and coronary angiogram and renal angiogram were also done. Based on variables, the chi-square test and t-test were employed to assess the significance. P-value < 0.05 was considered statistically significant. Results The mean age at presentation for patients with NSTEMI and hypertensive emergency was 58 years. Patients consuming alcohol were slightly higher (28, 28%) than those who smoked (23, 23%). Among all, 48 (48%) patients had diabetes. When considering the number of vessels, diabetic patients had more single-vessel diseases (18, 37.5%) and nondiabetic patients had more double-vessel diseases (15, 28.8%). The mean ejection fraction of the diabetic group was 56.1% ± 6.8% and the nondiabetic group was 54.2% ± 7.7%. Among all the patients, 52 (62.6%) used combination drugs, while 39 (46.9%) were on defaulter drugs. Conclusions Several risk factors like age, smoking, alcohol, and nonadherence to drugs were found to have an association with the occurrence of hypertensive emergency. Diabetes was found to be significantly associated with unfavorable coronary anatomy among the population.
摘要：
背景：高血压急症代表高心血管风险的情况，定义为血压的严重升高。与STEMI相比，非ST段抬高型心肌梗死（NSTEMI）中高血压的患病率更高，并且缺乏对NSTEMI伴高血压急症患者的研究。糖尿病患者的高血压急症发生率较高。本研究的主要目的是调查高血压急诊NSTEMI患者的冠状动脉疾病情况。次要目的是确定糖尿病对高血压急症发展的影响.方法本研究共纳入100例NSTEMI和高血压急症患者。研究的持续时间为24个月。患者也分为糖尿病和非糖尿病。注意到基线特征，还进行了冠状动脉造影和肾血管造影。根据变量，采用卡方检验和t检验评估显著性。P值<0.05被认为具有统计学意义。结果NSTEMI和高血压急症患者的平均年龄为58岁。饮酒的患者（28，28％）略高于吸烟的患者（23，23％）。其中,48例(48%)患者有糖尿病。当考虑到船只的数量时，糖尿病患者的单血管疾病较多(18,37.5%),非糖尿病患者的双血管疾病较多(15,28.8%).糖尿病组的平均射血分数为56.1％±6.8％，非糖尿病组为54.2％±7.7％。在所有的病人中,52（62.6%）使用联合用药，39人(46.9%)服用违约药物。结论几个危险因素，如年龄，吸烟,酒精,并且发现不坚持用药与高血压急症的发生有关.发现糖尿病与人群中不利的冠状动脉解剖结构显着相关。
