Diagnostic features of metastatic endometrioid carcinoma in a captive black-tufted marmoset (Callithrix penicillata).

圈养的黑色簇绒猴 （ Callithrix penicillata ） 中转移性子宫内膜样癌的诊断特征。

• 影响指数: 0.821
• 发表时间: 2024 Aug
• 来源期刊: J Med Primatol
• DOI: 10.1111/jmp.12727
• PMID: 39099092
• 文章类型: Case Reports
• 中科院分区: Q3;Q3
• 作者列表: de Macêdo IL,de Sousa DER,Mattioli M,Borges BP,Mendes de Lima EM,de Castro MB

关键词: Callithrix; estrogen receptor; immunohistochemistry; neoplasm; non‐human primates; reproductive system; uterine tumor

Mesh: Animals; Callithrix; Female; Carcinoma, Endometrioid / veterinary pathology diagnosis; Monkey Diseases / pathology diagnosis; Uterine Neoplasms / veterinary pathology diagnosis

Abstract

A captive marmoset developed metastatic endometrioid carcinoma (EnC), a rare uterine tumor in non-human primates (NHPs). The neoplasm showed marked microscopical malignant and tubulopapillary aspects, immunopositivity for pan-cytokeratin, CK7, estrogen receptor, and a high mitotic index (Ki-67). These features may contribute to the diagnosis and therapeutics of EnC in NHPs.

摘要

圈养的猕猴发展为转移性子宫内膜样癌（EnC），一种罕见的非人类灵长类动物子宫肿瘤（NHPs）。肿瘤显示明显的显微镜恶性和肾小管乳头状方面，泛细胞角蛋白的免疫阳性，CK7,雌激素受体,和高有丝分裂指数（Ki-67）。这些特征可能有助于NHP中EnC的诊断和治疗。