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Abstract：
Tuberculosis (TB) continues to pose a significant health challenge worldwide, emphasizing the importance of prompt diagnosis and efficient monitoring of treatment outcomes for effective disease control. Biomarkers have become increasingly important in the realm of TB diagnoses and treatment. The objective of this comprehensive review is to examine the present state of biomarkers employed in the diagnosis of TB, monitoring the response to treatment, and predicting treatment outcomes. In this study, we undertake a comprehensive examination of the diverse biomarkers utilized in TB diagnoses, spanning molecular, immunological, and other novel methodologies. Furthermore, we examine the potential of biomarkers in the context of therapeutic monitoring, assessment of treatment effectiveness, and anticipation of drug resistance. Additionally, this paper presents future prospects regarding the utilization of biomarkers in the therapy of tuberculosis.
摘要：
结核病（TB）继续在全球范围内构成重大的健康挑战，强调及时诊断和有效监测治疗结果以有效控制疾病的重要性。生物标志物在结核病诊断和治疗领域变得越来越重要。这篇综合综述的目的是研究结核病诊断中使用的生物标志物的现状，监测对治疗的反应，并预测治疗结果。在这项研究中,我们对结核病诊断中使用的各种生物标志物进行全面检查，跨越分子，免疫学，和其他新颖的方法。此外，我们研究了生物标志物在治疗监测方面的潜力，治疗效果评估，和耐药性的预期。此外,本文对生物标志物在结核病治疗中的应用前景进行了展望。
