Abstract：
UNASSIGNED: Catheter related thrombosis is a common complication of tunnelled central venous catheter (TCVC) usage. There are concerns that TCVC removal could dislodge a thrombus to cause pulmonary thromboembolism (PE). The incidence of PE following TCVC removal is unclear and so the aim of this study was to investigate the incidence of PE and whether it is high enough to warrant screening with ultrasound with a view to systemic anticoagulation prior to TCVC removal.
UNASSIGNED: 1102 consecutive TCVC removals without ultrasound and systemic anticoagulation were included in this retrospective study. Data were extracted from electronic health records. Measures to identify PE events included: deaths, computed tomography pulmonary angiogram (CT-PA), isotope lung perfusion scans and D-dimers blood tests within 7 days of removal.
UNASSIGNED: Of the 1102 TCVC removals, the mean age of patients was 56.9 years and 57.3% were male. The primary renal diagnosis for 24.5% of patients was diabetic nephropathy. There were seven deaths following removal, none of which had PE as a contributing cause on review of their clinical history and death certificates. Five CT-PAs and one isotope lung perfusion scan were carried out in the 7 days after TCVC removal and none had a positive finding of PE. Three patient had D-dimers measured in blood within 7 days and none of these patients were subsequently diagnosed with PE.
UNASSIGNED: There was no evidence of fatal or non-fatal PE\'s occurring in the 7 days following TCVC removal. This would support the practice of removing TCVCs without the need for ultrasound screening and without a period of systemic anticoagulation.
UNASSIGNED: 1102 consecutive TCVC removals without ultrasound and systemic anticoagulation were included in this retrospective study. Data were extracted from electronic health records. Measures to identify PE events included: deaths, computed tomography pulmonary angiogram (CT-PA), isotope lung perfusion scans and D-dimers blood tests within 7 days of removal.
UNASSIGNED: Of the 1102 TCVC removals, the mean age of patients was 56.9 years and 57.3% were male. The primary renal diagnosis for 24.5% of patients was diabetic nephropathy. There were seven deaths following removal, none of which had PE as a contributing cause on review of their clinical history and death certificates. Five CT-PAs and one isotope lung perfusion scan were carried out in the 7 days after TCVC removal and none had a positive finding of PE. Three patient had D-dimers measured in blood within 7 days and none of these patients were subsequently diagnosed with PE.
UNASSIGNED: There was no evidence of fatal or non-fatal PE\'s occurring in the 7 days following TCVC removal. This would support the practice of removing TCVCs without the need for ultrasound screening and without a period of systemic anticoagulation.
摘要：
■导管相关的血栓形成是隧道式中心静脉导管（TCVC）使用的常见并发症。人们担心去除TCVC可能会清除血栓以引起肺血栓栓塞（PE）。去除TCVC后PE的发生率尚不清楚，因此本研究的目的是调查PE的发生率以及是否足够高以保证在去除TCVC之前进行超声筛查以进行全身抗凝。
■本回顾性研究包括1102次连续的TCVC去除，没有超声和全身抗凝。数据是从电子健康记录中提取的。确定PE事件的措施包括：死亡，计算机断层扫描肺血管造影（CT-PA），去除后7天内进行同位素肺灌注扫描和D-二聚体血液测试。
■在1102次TCVC去除中，患者的平均年龄为56.9岁,57.3%为男性.24.5%的患者的主要肾脏诊断为糖尿病肾病。移除后有7人死亡，在回顾其临床病史和死亡证明时，没有一个以PE为促成因素。在去除TCVC后的7天内进行了五次CT-PAs和一次同位素肺灌注扫描，均未发现PE阳性。三名患者在7天内在血液中测量D-二聚体,并且这些患者中没有一个随后被诊断患有PE。
■在移除TCVC后的7天内，没有证据表明发生了致命的或非致命的PE。这将支持在不需要超声筛查和不需要一段时间的全身抗凝的情况下去除TCVCs的实践。
■本回顾性研究包括1102次连续的TCVC去除，没有超声和全身抗凝。数据是从电子健康记录中提取的。确定PE事件的措施包括：死亡，计算机断层扫描肺血管造影（CT-PA），去除后7天内进行同位素肺灌注扫描和D-二聚体血液测试。
■在1102次TCVC去除中，患者的平均年龄为56.9岁,57.3%为男性.24.5%的患者的主要肾脏诊断为糖尿病肾病。移除后有7人死亡，在回顾其临床病史和死亡证明时，没有一个以PE为促成因素。在去除TCVC后的7天内进行了五次CT-PAs和一次同位素肺灌注扫描，均未发现PE阳性。三名患者在7天内在血液中测量D-二聚体,并且这些患者中没有一个随后被诊断患有PE。
■在移除TCVC后的7天内，没有证据表明发生了致命的或非致命的PE。这将支持在不需要超声筛查和不需要一段时间的全身抗凝的情况下去除TCVCs的实践。
