Abstract：
BACKGROUND: Little is known about the relationship between body mass index (BMI), a function of mass and height (masskg/height2m) and long-term outcomes among traumatic injury survivors. In this prospective cohort study, we investigate the relationship between BMI and long-term health outcomes in the trauma population.
METHODS: Adult trauma survivors with an injury severity score ≥9 admitted to one of three level 1 trauma centers, from January 1, 2015 to December 31, 2022, were surveyed via telephone between 6 and 12 mo postinjury. Participants were stratified into one of five groups by BMI at the time of trauma: L-BMI (BMI <18.5), N-BMI (BMI 18.5-24.9), H1-BMI (BMI 25-29.9), H2-BMI (BMI 30-34.9), and H3-BMI (BMI ≥35); N-BMI was used as the referent. Mental and physical health-related quality of life scores, pain, new functional limitations, and hospital readmissions were evaluated. Univariate and multivariate analyses were used to compare outcomes between study groups.
RESULTS: 3830 patients were included. Of those, 124 were L-BMI (3.2%), 1495 N-BMI (39%), 1318 H1-BMI (34.4%), 541 H2-BMI (14.1%), and 352 H3-BMI (9.2%). L-BMI was associated with adverse physical (b = -3.13, CI = -5.71 to -0.55, P = 0.017) and mental health (b = -3.17, CI = -5.87 to -0.46, P = 0.022) outcomes 6-12 mo postinjury compared to the referent. H1-BMI and H2-BMI had higher odds of wo`rse physical outcomes (b = -1.47, CI = -2.42 to -0.52, P = 0.002; b = -3.11, CI = - 4.33 to -1.88, P ≤ 0.001, respectively) and chronic pain (adjusted odds ratio (aOR) = 1.24, CI = 1.04-1.47, P = 0.016; aOR = 1.52, CI = 1.21-1.90, P ≤ 0.001, respectively). Patients with H3-BMI had higher odds of worse physical outcomes compared to N-BMI (b = -4.82, CI = -6.28 to -3.37, P ≤ 0.001), chronic pain (aOR = 2.11, CI = 1.61-2.78, P ≤ 0.001), all-cause hospital readmissions (aOR = 1.62, CI = 1.10-2.34, P = 0.013), and new functional limitations (aOR = 1.39, CI = 1.08-1.79, P = 0.01).
CONCLUSIONS: BMI variance above or below N-BMI is associated with worse long-term outcomes following traumatic injury.
METHODS: Adult trauma survivors with an injury severity score ≥9 admitted to one of three level 1 trauma centers, from January 1, 2015 to December 31, 2022, were surveyed via telephone between 6 and 12 mo postinjury. Participants were stratified into one of five groups by BMI at the time of trauma: L-BMI (BMI <18.5), N-BMI (BMI 18.5-24.9), H1-BMI (BMI 25-29.9), H2-BMI (BMI 30-34.9), and H3-BMI (BMI ≥35); N-BMI was used as the referent. Mental and physical health-related quality of life scores, pain, new functional limitations, and hospital readmissions were evaluated. Univariate and multivariate analyses were used to compare outcomes between study groups.
RESULTS: 3830 patients were included. Of those, 124 were L-BMI (3.2%), 1495 N-BMI (39%), 1318 H1-BMI (34.4%), 541 H2-BMI (14.1%), and 352 H3-BMI (9.2%). L-BMI was associated with adverse physical (b = -3.13, CI = -5.71 to -0.55, P = 0.017) and mental health (b = -3.17, CI = -5.87 to -0.46, P = 0.022) outcomes 6-12 mo postinjury compared to the referent. H1-BMI and H2-BMI had higher odds of wo`rse physical outcomes (b = -1.47, CI = -2.42 to -0.52, P = 0.002; b = -3.11, CI = - 4.33 to -1.88, P ≤ 0.001, respectively) and chronic pain (adjusted odds ratio (aOR) = 1.24, CI = 1.04-1.47, P = 0.016; aOR = 1.52, CI = 1.21-1.90, P ≤ 0.001, respectively). Patients with H3-BMI had higher odds of worse physical outcomes compared to N-BMI (b = -4.82, CI = -6.28 to -3.37, P ≤ 0.001), chronic pain (aOR = 2.11, CI = 1.61-2.78, P ≤ 0.001), all-cause hospital readmissions (aOR = 1.62, CI = 1.10-2.34, P = 0.013), and new functional limitations (aOR = 1.39, CI = 1.08-1.79, P = 0.01).
CONCLUSIONS: BMI variance above or below N-BMI is associated with worse long-term outcomes following traumatic injury.
摘要：
背景：关于体重指数（BMI）之间的关系知之甚少，创伤幸存者的质量和身高（masskg/height2m）以及长期结局的函数。在这项前瞻性队列研究中，我们调查了创伤人群BMI与长期健康结局之间的关系.
方法：受伤严重程度评分≥9分的成年创伤幸存者入住三个一级创伤中心之一，从2015年1月1日至2022年12月31日，在受伤后6至12个月之间通过电话进行了调查。根据创伤时的BMI将参与者分为五组之一：L-BMI（BMI<18.5），N-BMI（BMI18.5-24.9），H1-BMI（BMI25-29.9），H2-BMI（BMI30-34.9），和H3-BMI（BMI≥35）；N-BMI用作参考。精神和身体健康相关的生活质量评分，疼痛,新的功能限制，并评估了再入院率.使用单变量和多变量分析比较研究组之间的结果。
结果：纳入3830例患者。其中,124为L-BMI（3.2%），1495N-BMI（39%），1318H1-BMI（34.4%），541H2-BMI（14.1%），和352H3-BMI（9.2％）。L-BMI与伤后6-12个月的不良身体（b=-3.13，CI=-5.71至-0.55，P=0.017）和心理健康（b=-3.17，CI=-5.87至-0.46，P=0.022）结果相关。H1-BMI和H2-BMI具有较高的物理结果（b=-1.47，CI=-2.42至-0.52，P=0.002;b=-3.11，CI=-4.33至-1.88，P≤0.001，分别）和慢性疼痛（调整比值比（aOR）=1.24，CI=1.04-1.47，P=0.016；aOR=1.52，CI=1.21与N-BMI相比，H3-BMI患者的身体预后较差的可能性更高（b=-4.82，CI=-6.28至-3.37，P≤0.001），慢性疼痛（aOR=2.11，CI=1.61-2.78，P≤0.001），全因再入院（aOR=1.62，CI=1.10-2.34，P=0.013），和新的功能限制（aOR=1.39，CI=1.08-1.79，P=0.01）。
结论：BMI方差高于或低于N-BMI与创伤性损伤后较差的长期预后相关。
方法：受伤严重程度评分≥9分的成年创伤幸存者入住三个一级创伤中心之一，从2015年1月1日至2022年12月31日，在受伤后6至12个月之间通过电话进行了调查。根据创伤时的BMI将参与者分为五组之一：L-BMI（BMI<18.5），N-BMI（BMI18.5-24.9），H1-BMI（BMI25-29.9），H2-BMI（BMI30-34.9），和H3-BMI（BMI≥35）；N-BMI用作参考。精神和身体健康相关的生活质量评分，疼痛,新的功能限制，并评估了再入院率.使用单变量和多变量分析比较研究组之间的结果。
结果：纳入3830例患者。其中,124为L-BMI（3.2%），1495N-BMI（39%），1318H1-BMI（34.4%），541H2-BMI（14.1%），和352H3-BMI（9.2％）。L-BMI与伤后6-12个月的不良身体（b=-3.13，CI=-5.71至-0.55，P=0.017）和心理健康（b=-3.17，CI=-5.87至-0.46，P=0.022）结果相关。H1-BMI和H2-BMI具有较高的物理结果（b=-1.47，CI=-2.42至-0.52，P=0.002;b=-3.11，CI=-4.33至-1.88，P≤0.001，分别）和慢性疼痛（调整比值比（aOR）=1.24，CI=1.04-1.47，P=0.016；aOR=1.52，CI=1.21与N-BMI相比，H3-BMI患者的身体预后较差的可能性更高（b=-4.82，CI=-6.28至-3.37，P≤0.001），慢性疼痛（aOR=2.11，CI=1.61-2.78，P≤0.001），全因再入院（aOR=1.62，CI=1.10-2.34，P=0.013），和新的功能限制（aOR=1.39，CI=1.08-1.79，P=0.01）。
结论：BMI方差高于或低于N-BMI与创伤性损伤后较差的长期预后相关。
