Abstract：
The association between live microbe intake and osteoporosis in postmenopausal women remains unknown. The research findings indicated that an increased intake of live microbes through dietary sources was associated with a low prevalence of osteoporosis among postmenopausal women.
OBJECTIVE: To investigate the relationship between the consumption of live microbes in the diet and osteoporosis in postmenopausal women.
METHODS: A cross-sectional investigation using data obtained from the National Health and Nutrition Examination Survey was conducted. Participants were classified into three groups by using the dietary live microbe classification system developed by Sanders. Dual x-ray absorptiometry was used to measure body mineral density, and osteoporosis was diagnosed according to the World Health Organization criteria. We conducted a crude and adjusted multivariate logistic regression analysis, and utilized the restricted cubic splines model to assess the correlation between the consumption of live microbes in the diet and osteoporosis in postmenopausal women.
RESULTS: A total of 1378 women who had undergone menopause were enrolled in the study. After controlling for potential covariates, individuals with a high consumption of live microbes in their diet exhibited a notably low prevalence of osteoporosis in comparison to those with a low intake of dietary live microbes (odd ratio: 0.46, 95% confidence interval: 0.23, 0.93, P = 0.03). Subgroup analysis showed the stability of the results, and restricted cubic splines showed an approximate L-shape curve.
CONCLUSIONS: In this research, a higher consumption of live microbes in the diet was linked to a low prevalence of osteoporosis in postmenopausal women.
OBJECTIVE: To investigate the relationship between the consumption of live microbes in the diet and osteoporosis in postmenopausal women.
METHODS: A cross-sectional investigation using data obtained from the National Health and Nutrition Examination Survey was conducted. Participants were classified into three groups by using the dietary live microbe classification system developed by Sanders. Dual x-ray absorptiometry was used to measure body mineral density, and osteoporosis was diagnosed according to the World Health Organization criteria. We conducted a crude and adjusted multivariate logistic regression analysis, and utilized the restricted cubic splines model to assess the correlation between the consumption of live microbes in the diet and osteoporosis in postmenopausal women.
RESULTS: A total of 1378 women who had undergone menopause were enrolled in the study. After controlling for potential covariates, individuals with a high consumption of live microbes in their diet exhibited a notably low prevalence of osteoporosis in comparison to those with a low intake of dietary live microbes (odd ratio: 0.46, 95% confidence interval: 0.23, 0.93, P = 0.03). Subgroup analysis showed the stability of the results, and restricted cubic splines showed an approximate L-shape curve.
CONCLUSIONS: In this research, a higher consumption of live microbes in the diet was linked to a low prevalence of osteoporosis in postmenopausal women.
摘要：
绝经后妇女的活微生物摄入量与骨质疏松症之间的关系仍然未知。研究结果表明，通过饮食来源增加活微生物的摄入量与绝经后妇女骨质疏松症的低患病率有关。
目的：探讨绝经后妇女饮食中活微生物的摄入与骨质疏松的关系。
方法：使用从国家健康和营养调查获得的数据进行了横断面调查。通过使用Sanders开发的饮食活微生物分类系统，将参与者分为三组。使用双X射线吸收法测量人体矿物质密度，根据世界卫生组织的标准诊断出骨质疏松症。我们进行了粗略和调整后的多变量逻辑回归分析，并利用限制性三次样条模型来评估绝经后妇女饮食中活微生物的消耗与骨质疏松症之间的相关性。
结果：共有1378名经历过绝经期的妇女参加了这项研究。在控制潜在协变量后，与饮食中活微生物摄入量低的个体相比,饮食中活微生物摄入量高的个体骨质疏松症患病率明显较低(奇数比:0.46,95%置信区间:0.23,0.93,P=0.03).亚组分析显示结果的稳定性,和限制三次样条显示近似L形曲线。
结论：在这项研究中，饮食中活微生物摄入量较高与绝经后妇女骨质疏松症患病率较低有关.
目的：探讨绝经后妇女饮食中活微生物的摄入与骨质疏松的关系。
方法：使用从国家健康和营养调查获得的数据进行了横断面调查。通过使用Sanders开发的饮食活微生物分类系统，将参与者分为三组。使用双X射线吸收法测量人体矿物质密度，根据世界卫生组织的标准诊断出骨质疏松症。我们进行了粗略和调整后的多变量逻辑回归分析，并利用限制性三次样条模型来评估绝经后妇女饮食中活微生物的消耗与骨质疏松症之间的相关性。
结果：共有1378名经历过绝经期的妇女参加了这项研究。在控制潜在协变量后，与饮食中活微生物摄入量低的个体相比,饮食中活微生物摄入量高的个体骨质疏松症患病率明显较低(奇数比:0.46,95%置信区间:0.23,0.93,P=0.03).亚组分析显示结果的稳定性,和限制三次样条显示近似L形曲线。
结论：在这项研究中，饮食中活微生物摄入量较高与绝经后妇女骨质疏松症患病率较低有关.
