关键词: Chronic wound essential oil herbal extract nanotechnology phytoconstituent wound dressing

Mesh : Wound Healing / drug effects Humans Animals Bandages Nanotechnology Drug Delivery Systems Plant Extracts / administration & dosage pharmacology Plant Preparations / administration & dosage therapeutic use Oils, Volatile / administration & dosage therapeutic use Nanocomposites / chemistry Wounds and Injuries / drug therapy therapy

来  源:   DOI:10.1080/17425247.2024.2388214

Abstract:
UNASSIGNED: Wound healing is an intricate and continual process influenced by numerous factors that necessitate suitable environments to attain healing. The natural ability of wound healing often gets altered by several external and intrinsic factors, leading to chronic wound occurrence. Numerous wound dressings have been developed; however, the currently available alternatives fail to coalesce in all conditions obligatory for rapid skin regeneration.
UNASSIGNED: An extensive review of articles on herbal nano-composite wound dressings was conducted using PubMed, Scopus, and Google Scholar databases, from 2006 to 2024. This review entails the pathophysiology and factors leading to non-healing wounds, wound dressing types, the role of herbal bio-actives for wound healing, and the advantages of employing nanotechnology to deliver herbal actives. Numerous nano-composite wound dressings incorporated with phytoconstituents, herbal extracts, and essential oils are discussed.
UNASSIGNED: There is a strong substantiation that several herbal bio-actives possess anti-inflammatory, antimicrobial, antioxidant, analgesic, and angiogenesis promoter activities that accelerate the wound healing process. Nanotechnology is a promising strategy to deliver herbal bio-actives as it ascertains their controlled release, enhances bioavailability, improves permeability to underlying skin layers, and promotes wound healing. A combination of herbal actives and nano-based dressings offers a novel arena for wound management.
摘要:
伤口愈合是一个复杂且连续的过程,受许多因素的影响,这些因素需要合适的环境来实现愈合。伤口愈合的自然能力经常被几个外部和内在因素改变,导致慢性伤口的发生。已经开发了许多伤口敷料,然而,目前可用的替代品无法合并所有必须快速皮肤再生的条件。
使用PubMed对有关草药纳米复合伤口敷料的文章进行了广泛的评论,Scopus,和谷歌学者数据库,从2006年到2024年。这篇综述涉及导致伤口不愈合的病理生理学和因素,伤口敷料类型,草药生物活性物质对伤口愈合的作用,以及采用纳米技术提供草药活性物质的优势。许多纳米复合伤口敷料掺入植物成分,草药提取物,和精油进行了讨论。
有一个强有力的证据表明,几种草药生物活性物质具有抗炎作用,抗菌,抗氧化剂,镇痛药,和加速伤口愈合过程的血管生成促进剂活性。纳米技术是一个有前途的战略,以提供草药生物活性,因为它确定他们的控制释放,提高生物利用度,改善对底层皮肤层的渗透性,促进伤口愈合.草药活性物质和基于纳米的敷料的组合为伤口管理提供了新的场所。
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