磷酸二酯酶 5 型抑制剂他达拉非通过 MiR - 3126 - 3p / FGF9 轴减少良性前列腺增生中的前列腺纤维化.
关键词: Benign prostatic hyperplasia FGF9 Myofibroblast differentiation Phosphodiesterase 5 inhibitor miR-3126-3p
Mesh : Male Prostatic Hyperplasia / metabolism drug therapy genetics MicroRNAs / genetics metabolism Tadalafil / pharmacology Phosphodiesterase 5 Inhibitors / pharmacology Humans Fibrosis Fibroblast Growth Factor 9 / metabolism genetics Prostate / drug effects metabolism Myofibroblasts / metabolism drug effects Transforming Growth Factor beta1 / metabolism genetics Cell Proliferation / drug effects
来 源:
DOI:10.1186/s13062-024-00504-y
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