Abstract:
Dry powder inhalers (DPIs) are state-of-the-art pulmonary drug delivery systems. This article explores the transformative impact of nanotechnology on DPIs, emphasizing the Quality Target Product Profile (QTPP) with a focus on aerodynamic performance and particle characteristics. It navigates global regulatory frameworks, underscoring the need for safety and efficacy standards. Additionally, it highlights the emerging field of nanoparticulate dry powder inhalers, showcasing their potential to enhance targeted drug delivery in respiratory medicine. This concise overview is a valuable resource for researchers, physicians, and pharmaceutical developers, providing insights into the development and commercialization of advanced inhalation systems.
摘要:
干粉吸入器(DPI)是最先进的肺部药物递送系统。本文探讨了纳米技术对DPI的变革性影响,强调质量目标产品概况(QTPP),重点关注空气动力学性能和颗粒特性。它导航全球监管框架,强调安全性和有效性标准的必要性。此外,它突出了纳米颗粒干粉吸入器的新兴领域,展示了它们在呼吸医学中增强靶向药物递送的潜力。这个简明的概述是研究人员的宝贵资源,医师,和药物开发商,提供对先进吸入系统的开发和商业化的见解。