Abstract：
Microsporidia are opportunistic fungal-like pathogens that cause microsporidiosis, which results in significant economic losses and threatens public health. Infection of domesticated silkworms by the microsporidium Nosema bombycis causes pébrine disease, for which this species of microsporidia has received much attention. Research has been conducted extensively on this microsporidium over the past few decades to better understand its infection, transmission, host-parasite interaction, and detection. Several tools exist to study this species including the complete genome sequence of N. bombycis. In addition to the understanding of N. bombycis being important for the silkworm industry, this species has become a model organism for studying microsporidia. Research on biology of N. bombycis will contribute to the development of knowledge regarding microsporidia and potential antimicrosporidia drugs. Furthermore, this will provide insight into the molecular evolution and functioning of other fungal pathogens.
摘要：
微孢子虫是导致微孢子虫病的机会性真菌样病原体，造成重大经济损失，威胁公众健康。家蚕微孢子虫感染家蚕会引起pébrine病，这种微孢子虫受到了很多关注。在过去的几十年中，人们对这种微孢子虫进行了广泛的研究，以更好地了解其感染情况，传输,宿主-寄生虫相互作用，和检测。存在几种工具来研究该物种，包括N.bombycis的完整基因组序列。除了对N.Bombycis的理解对蚕业很重要之外，该物种已成为研究微孢子虫的模型生物。对N.bombycis生物学的研究将有助于发展有关微孢子虫和潜在的抗微孢子虫药物的知识。此外，这将有助于深入了解其他真菌病原体的分子进化和功能。
