Abstract：
High-flow nasal therapy (HFNT) has an increasing role in the management of acute hypoxic respiratory failure. Due to its tolerable interface and ease of use, its role in chronic hypercapnic respiratory failure (CHRF) is emerging. This article examines the literature to date surrounding the short and long-term mechanisms of HFNT in sleep and wakefulness of CHRF patients. It is likely HFNT will have an increasing role in those patients intolerant of non-invasive ventilation.
摘要：
高流量鼻腔治疗（HFNT）在急性低氧性呼吸衰竭的治疗中具有越来越重要的作用。由于其可容忍的界面和易用性，其在慢性高碳酸血症性呼吸衰竭（CHRF）中的作用正在出现。本文研究了迄今为止有关HFNT在CHRF患者睡眠和觉醒中的短期和长期机制的文献。HFNT可能在那些不耐受无创通气的患者中发挥越来越大的作用。
