Abstract：
This review provides an up-to-date summary of the prevalence, pathophysiology, diagnosis, and treatment of the chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) overlap syndrome (OVS). The presence of OVS is high in patients with COPD and in patients with OSA and is associated with profound nocturnal oxygen desaturation and systemic inflammation. There is a high prevalence of cardiovascular disease among patients with OVS and this likely contributes to increased mortality. Observational studies suggest that positive airway pressure therapy improves survival and reduces COPD exacerbations; however, randomized controlled trials will be required to confirm these findings.
摘要：
这篇综述提供了患病率的最新摘要，病理生理学,诊断,并治疗慢性阻塞性肺疾病（COPD）和阻塞性睡眠呼吸暂停（OSA）重叠综合征（OVS）。在COPD患者和OSA患者中OVS的存在较高,并且与深夜间氧饱和度和全身性炎症相关。OVS患者中心血管疾病的患病率很高，这可能导致死亡率增加。观察性研究表明，气道正压通气治疗可提高生存率，减少COPD加重；然而，需要随机对照试验来证实这些发现.
