PDF(Pubmed)
Abstract：
BACKGROUND: Diffuse intestinal and mesenteric lipomatosis is a rare condition characterized by the overgrowth of adipose tissue in the intestines and mesentery. This case report aims to highlight the rare occurrence of chronic abdominal distention caused by this disease and its unique invasion into the muscle layer, which has not been previously reported.
METHODS: A 36-year-old woman with a 7-year history of abdominal distension was admitted to our hospital\'s Department of Gastrointestinal Surgery.
METHODS: Abdominal and pelvic computed tomography revealed diffuse small intestinal lipomatosis.
METHODS: The patient underwent surgery. We performed an open-field ilectomy involving removal of all lipomatous intestines (250 cm).
RESULTS: During the surgery, diffuse nodular ileal and mesenteric lipomatosis was confirmed, characterized by the presence of multiple nodular lipomas within the submucosal and muscular layers. The surgical intervention involved the resection of 250 cm of the affected ileum, followed by jejunoileal anastomosis. Postoperative pathology confirmed the diagnosis, with lesions observed in both the submucosa and muscle layers. The patient showed significant improvement in symptoms, with normal intestinal function and weight gain observed over a 10-month follow-up period, and no signs of recurrence.
CONCLUSIONS: Diffuse intestinal and mesenteric lipomatosis can lead to long-term abdominal distension. Additionally, it may be involved in the muscle layer of the intestinal wall. Surgery is the primary treatment option for symptomatic intestinal lipomatosis.
METHODS: A 36-year-old woman with a 7-year history of abdominal distension was admitted to our hospital\'s Department of Gastrointestinal Surgery.
METHODS: Abdominal and pelvic computed tomography revealed diffuse small intestinal lipomatosis.
METHODS: The patient underwent surgery. We performed an open-field ilectomy involving removal of all lipomatous intestines (250 cm).
RESULTS: During the surgery, diffuse nodular ileal and mesenteric lipomatosis was confirmed, characterized by the presence of multiple nodular lipomas within the submucosal and muscular layers. The surgical intervention involved the resection of 250 cm of the affected ileum, followed by jejunoileal anastomosis. Postoperative pathology confirmed the diagnosis, with lesions observed in both the submucosa and muscle layers. The patient showed significant improvement in symptoms, with normal intestinal function and weight gain observed over a 10-month follow-up period, and no signs of recurrence.
CONCLUSIONS: Diffuse intestinal and mesenteric lipomatosis can lead to long-term abdominal distension. Additionally, it may be involved in the muscle layer of the intestinal wall. Surgery is the primary treatment option for symptomatic intestinal lipomatosis.
摘要：
背景：弥漫性肠道和肠系膜脂肪瘤病是一种罕见的疾病，其特征是肠道和肠系膜脂肪组织过度生长。该病例报告旨在强调这种疾病引起的慢性腹胀的罕见发生及其对肌肉层的独特侵袭，以前没有报道过。
方法：我院胃肠外科收治一名36岁女性，有7年腹胀病史。
方法：腹部和盆腔CT显示弥漫性小肠脂肪瘤病。
方法：患者接受了手术。我们进行了开放野切除术，包括切除所有脂肪瘤肠（250厘米）。
结果：在手术过程中，弥漫性结节性回肠和肠系膜脂肪瘤病得到证实，以粘膜下层和肌肉层内存在多发性结节性脂肪瘤为特征。手术干预涉及切除250厘米的受影响回肠，然后空肠吻合术.术后病理证实诊断，在粘膜下层和肌肉层都观察到病变。患者症状明显改善,在10个月的随访期内观察到正常的肠道功能和体重增加，也没有复发的迹象.
结论：弥漫性肠道和肠系膜脂肪瘤病可导致长期腹胀。此外,它可能涉及肠壁的肌肉层。手术是症状性肠脂肪瘤病的主要治疗选择。
方法：我院胃肠外科收治一名36岁女性，有7年腹胀病史。
方法：腹部和盆腔CT显示弥漫性小肠脂肪瘤病。
方法：患者接受了手术。我们进行了开放野切除术，包括切除所有脂肪瘤肠（250厘米）。
结果：在手术过程中，弥漫性结节性回肠和肠系膜脂肪瘤病得到证实，以粘膜下层和肌肉层内存在多发性结节性脂肪瘤为特征。手术干预涉及切除250厘米的受影响回肠，然后空肠吻合术.术后病理证实诊断，在粘膜下层和肌肉层都观察到病变。患者症状明显改善,在10个月的随访期内观察到正常的肠道功能和体重增加，也没有复发的迹象.
结论：弥漫性肠道和肠系膜脂肪瘤病可导致长期腹胀。此外,它可能涉及肠壁的肌肉层。手术是症状性肠脂肪瘤病的主要治疗选择。
