PDF(Pubmed)
Abstract：
UNASSIGNED: Lung adenocarcinoma may resemble the clinical presentation of an infectious or inflammatory lung disease. The coexistence of lung cancer, and polyserous effusions is uncommon, which may cause a diagnostic challenge. However, any polyserous effusions at a young age must always be suspicious for malignancy.
METHODS: We report a case of 38-year-old male patient with polyserous effusions and pneumonia who was treated accordingly and showed clinical improvement with a significant reduction of pericardial and pleural effusions. Subsequent testing and a biopsy resulted in the histopathological diagnosis of an adenocarcinoma of the lung.
UNASSIGNED: Nonrecurrent polyserous effusions in lung adenocarcinoma are uncommon, and negative cytology results may not exclude malignancy due to the moderate sensitivity of pleural and pericardial fluid cytology. Clinicians should remain vigilant for false-negative results, especially in younger patients. Malignancy should not be ruled out because pleural and pericardial fluid cytology have a sensitivity of 60% and 92%, respectively.
CONCLUSIONS: Our case highlights the diagnostic challenges posed by atypical presentations of lung adenocarcinoma and emphasizes the importance of considering malignancy in the differential diagnosis of polyserous effusions, even when initial cytology results are negative. Clarifying the rationale for this study enhances its relevance and impact.
METHODS: We report a case of 38-year-old male patient with polyserous effusions and pneumonia who was treated accordingly and showed clinical improvement with a significant reduction of pericardial and pleural effusions. Subsequent testing and a biopsy resulted in the histopathological diagnosis of an adenocarcinoma of the lung.
UNASSIGNED: Nonrecurrent polyserous effusions in lung adenocarcinoma are uncommon, and negative cytology results may not exclude malignancy due to the moderate sensitivity of pleural and pericardial fluid cytology. Clinicians should remain vigilant for false-negative results, especially in younger patients. Malignancy should not be ruled out because pleural and pericardial fluid cytology have a sensitivity of 60% and 92%, respectively.
CONCLUSIONS: Our case highlights the diagnostic challenges posed by atypical presentations of lung adenocarcinoma and emphasizes the importance of considering malignancy in the differential diagnosis of polyserous effusions, even when initial cytology results are negative. Clarifying the rationale for this study enhances its relevance and impact.
摘要：
■肺腺癌可能类似于感染性或炎症性肺病的临床表现。肺癌的共存，多浆液性积液并不常见，这可能会导致诊断挑战。然而,任何年轻时的多浆液性积液都必须始终怀疑恶性肿瘤。
方法：我们报告了一例38岁的男性患者，患有多浆液性积液和肺炎，经过相应的治疗，临床症状得到改善，心包和胸腔积液明显减少。随后的测试和活检导致肺腺癌的组织病理学诊断。
■非复发性多浆液性积液在肺腺癌中并不常见，由于胸膜和心包液细胞学的中度敏感性，细胞学结果阴性可能不能排除恶性肿瘤。临床医生应该对假阴性结果保持警惕，尤其是年轻患者。不应排除恶性，因为胸膜和心包液细胞学的敏感性分别为60%和92%。分别。
结论：我们的病例强调了肺腺癌的非典型表现带来的诊断挑战，并强调了在多浆液性积液的鉴别诊断中考虑恶性的重要性。即使初始细胞学结果为阴性。澄清这项研究的理由可以增强其相关性和影响力。
方法：我们报告了一例38岁的男性患者，患有多浆液性积液和肺炎，经过相应的治疗，临床症状得到改善，心包和胸腔积液明显减少。随后的测试和活检导致肺腺癌的组织病理学诊断。
■非复发性多浆液性积液在肺腺癌中并不常见，由于胸膜和心包液细胞学的中度敏感性，细胞学结果阴性可能不能排除恶性肿瘤。临床医生应该对假阴性结果保持警惕，尤其是年轻患者。不应排除恶性，因为胸膜和心包液细胞学的敏感性分别为60%和92%。分别。
结论：我们的病例强调了肺腺癌的非典型表现带来的诊断挑战，并强调了在多浆液性积液的鉴别诊断中考虑恶性的重要性。即使初始细胞学结果为阴性。澄清这项研究的理由可以增强其相关性和影响力。
