Abstract：
BACKGROUND: Acne vulgaris is a complex, multifactorial, inflammatory skin condition. Although frequently presented at dermatology clinics, the literature on adult acne is scarce, particularly concerning skin barrier function and management. We aimed to provide insights into the role of skin barrier integrity in adult acne patients and the role of cleansers and moisturizers as adjunctive to treating and maintaining adult acne. Methods: A panel of eight dermatologists who treat adult patients with acne developed a consensus paper on the role of skin barrier function and skin care in adult acne management. The modified Delphi method comprised a face-to-face meeting and online follow-up to discuss the results of a scoping literature review. Drawing from their experience and opinions, they agreed on seven consensus statements. Results: Epidermal barrier dysfunction plays a vital role in acne pathogenesis and asymmetrically impacts adult female acne. Erythema, pruritus, peeling, and xerosis are common adverse effects of first-line acne treatment options and, if not appropriately counseled and managed, can exacerbate, leading to regimen nonadherence and poor patient experience and outcomes.
CONCLUSIONS: Improving patient knowledge of comprehensive acne treatments, including quality adjunctive cleansers and moisturizers, may maximize regimen efficacy and provide patients with personalized and successful acne treatment and maintenance tools. J Drugs Dermatol. 2024;23(8):674-679. doi:10.36849/JDD.8471.
CONCLUSIONS: Improving patient knowledge of comprehensive acne treatments, including quality adjunctive cleansers and moisturizers, may maximize regimen efficacy and provide patients with personalized and successful acne treatment and maintenance tools. J Drugs Dermatol. 2024;23(8):674-679. doi:10.36849/JDD.8471.
摘要：
背景：寻常痤疮是一种复杂的，多因素，炎性皮肤状况。尽管经常出现在皮肤科诊所，关于成人痤疮的文献很少，特别是关于皮肤屏障功能和管理。我们旨在深入了解成人痤疮患者皮肤屏障完整性的作用以及清洁剂和保湿剂作为治疗和维持成人痤疮的辅助作用。方法：由八名治疗成人痤疮患者的皮肤科医生组成的小组就皮肤屏障功能和皮肤护理在成人痤疮管理中的作用发表了一份共识论文。改进的德尔菲法包括面对面会议和在线随访，以讨论范围界定文献综述的结果。根据他们的经验和意见，他们同意了七个协商一致的声明。结果：表皮屏障功能障碍在痤疮发病机制中起着至关重要的作用，并且不对称地影响成年女性痤疮。红斑,瘙痒,剥皮,和干燥症是一线痤疮治疗方案的常见不良反应，如果没有适当的咨询和管理，会加剧，导致治疗方案不依从性和不良的患者体验和结果。
结论：提高患者对综合痤疮治疗的认识，包括优质的辅助清洁剂和保湿剂，可以最大限度地提高治疗方案的疗效，并为患者提供个性化和成功的痤疮治疗和维护工具。J药物Dermatol.2024；23（8）：674–679。doi:10.36849/JDD.8471。
结论：提高患者对综合痤疮治疗的认识，包括优质的辅助清洁剂和保湿剂，可以最大限度地提高治疗方案的疗效，并为患者提供个性化和成功的痤疮治疗和维护工具。J药物Dermatol.2024；23（8）：674–679。doi:10.36849/JDD.8471。
