Abstract：
To review current literature and synthesize clinical outcomes related to different low-level laser techniques as a complement to basic periodontal therapy (BPT). Electronic searches were conducted in PubMed, Cochrane, and Scopus, and clinical trials published from January 2013 to August 2023 using photobiomodulation as a complement to basic periodontal therapy, with a clear description of the laser technique, were included. The risk of bias was assessed using the Joanna Briggs Institute Critical Assessment Checklist. Estimates of interest were calculated using random effects meta-analyses. A total of 947 references were retrieved, and 22 studies were included for qualitative synthesis. Ten studies used intrasulcular laser techniques, with 89% using infrared wavelength, and 12 studies used transgingival techniques, with 61.5% using red wavelength. The frequency of photobiomodulation after BPT ranged from 1 to 9 sessions, with follow-up periods ranging from 5 days to 12 months. Risk of bias was considered low in 16 studies and moderate in six studies. Meta-analysis of 13 studies showed that BPT reduced probing depth at 4-, 12- and 24-weeks post-treatment, and improved clinical level attachment at 6-, 12- and 24-weeks post-treatment. Studies suggest that photobiomodulation may be a valuable complement in the treatment of periodontitis, especially using transgingival application technique.
摘要：
回顾当前文献并综合与不同低水平激光技术相关的临床结果，以补充基础牙周治疗（BPT）。在PubMed进行了电子搜索，科克伦,还有Scopus,以及2013年1月至2023年8月发表的使用光生物调节作为基础牙周治疗补充的临床试验，清楚地描述了激光技术，包括在内。使用JoannaBriggs研究所关键评估清单评估偏倚风险。使用随机效应荟萃分析计算感兴趣的估计值。共检索到947个参考文献，共纳入22项研究进行定性综合。十项研究使用了腔内激光技术，89%使用红外波长，和12项研究使用跨牙龈技术，61.5%使用红色波长。BPT后光生物调节的频率范围为1至9个疗程，随访期从5天到12个月不等。在16项研究中，偏倚风险被认为是低的，在6项研究中被认为是中等的。13项研究的荟萃分析表明，BPT在4-，治疗后12周和24周，并在6-，治疗后12周和24周。研究表明，光生物调节可能是治疗牙周炎的一种有价值的补充，特别是使用跨牙龈应用技术。
