PDF(Pubmed)
Abstract：
The oral microbiome potentially wields significant influence in the development of cancer. Within the human oral cavity, an impressive diversity of more than 700 bacterial species resides, making it the second most varied microbiome in the body. This finely balanced oral microbiome ecosystem is vital for sustaining oral health. However, disruptions in this equilibrium, often brought about by dietary habits and inadequate oral hygiene, can result in various oral ailments like periodontitis, cavities, gingivitis, and even oral cancer. There is compelling evidence that the oral microbiome is linked to several types of cancer, including oral, pancreatic, colorectal, lung, gastric, and head and neck cancers. This review discussed the critical connections between cancer and members of the human oral microbiota. Extensive searches were conducted across the Web of Science, Scopus, and PubMed databases to provide an up-to-date overview of our understanding of the oral microbiota\'s role in various human cancers. By understanding the possible microbial origins of carcinogenesis, healthcare professionals can diagnose neoplastic diseases earlier and design treatments accordingly.
Interactions between oral microbiota shifts and cancer: The oral microbiome potentially wields significant influence in the development of cancer. Within the human oral cavity, an impressive diversity of more than 700 bacterial species resides, making it the second most varied microbiome in the body. This finely balanced oral microbiome ecosystem is vital for sustaining oral health. However, disruptions in this equilibrium, often brought about by dietary habits and inadequate oral hygiene, can result in various oral ailments like periodontitis, cavities, gingivitis, and even oral cancer. There is compelling evidence that the oral microbiome is linked to several types of cancer, including oral, pancreatic, colorectal, lung, gastric, and head and neck cancers. This review discussed the critical connections between cancer and members of the human oral microbiota. Extensive searches were conducted across the Web of Science, Scopus, and PubMed databases to provide an up-to-date overview of our understanding of the oral microbiota\'s role in various human cancers. By understanding the possible microbial origins of carcinogenesis, healthcare professionals can diagnose neoplastic diseases earlier and design treatments accordingly.
Interactions between oral microbiota shifts and cancer: The oral microbiome potentially wields significant influence in the development of cancer. Within the human oral cavity, an impressive diversity of more than 700 bacterial species resides, making it the second most varied microbiome in the body. This finely balanced oral microbiome ecosystem is vital for sustaining oral health. However, disruptions in this equilibrium, often brought about by dietary habits and inadequate oral hygiene, can result in various oral ailments like periodontitis, cavities, gingivitis, and even oral cancer. There is compelling evidence that the oral microbiome is linked to several types of cancer, including oral, pancreatic, colorectal, lung, gastric, and head and neck cancers. This review discussed the critical connections between cancer and members of the human oral microbiota. Extensive searches were conducted across the Web of Science, Scopus, and PubMed databases to provide an up-to-date overview of our understanding of the oral microbiota\'s role in various human cancers. By understanding the possible microbial origins of carcinogenesis, healthcare professionals can diagnose neoplastic diseases earlier and design treatments accordingly.
摘要：
口腔微生物组可能对癌症的发展产生重大影响。在人类口腔内，超过700种细菌的多样性令人印象深刻，使其成为体内第二大变化的微生物组。这种良好平衡的口腔微生物组生态系统对于维持口腔健康至关重要。然而,这种平衡的破坏，通常由饮食习惯和口腔卫生不足引起，会导致各种口腔疾病，如牙周炎，空腔,牙龈炎,甚至口腔癌。有令人信服的证据表明口腔微生物与几种类型的癌症有关，包括口服,胰腺,结直肠,肺，胃,头颈癌.这篇综述讨论了癌症与人类口腔微生物群成员之间的关键联系。在科学网进行了广泛的搜索，Scopus,和PubMed数据库提供了我们对口腔微生物群在各种人类癌症中的作用的理解的最新概述。通过了解致癌的可能的微生物起源，医疗保健专业人员可以更早地诊断肿瘤疾病，并相应地设计治疗方法。
口腔微生物群变化与癌症之间的相互作用：口腔微生物群对癌症的发展可能产生重大影响。在人类口腔内，超过700种细菌的多样性令人印象深刻，使其成为体内第二大变化的微生物组。这种良好平衡的口腔微生物组生态系统对于维持口腔健康至关重要。然而,这种平衡的破坏，通常由饮食习惯和口腔卫生不足引起，会导致各种口腔疾病，如牙周炎，空腔,牙龈炎,甚至口腔癌。有令人信服的证据表明口腔微生物与几种类型的癌症有关，包括口服,胰腺,结直肠,肺，胃,头颈癌.这篇综述讨论了癌症与人类口腔微生物群成员之间的关键联系。在科学网进行了广泛的搜索，Scopus,和PubMed数据库提供了我们对口腔微生物群在各种人类癌症中的作用的理解的最新概述。通过了解致癌的可能的微生物起源，医疗保健专业人员可以更早地诊断肿瘤疾病，并相应地设计治疗方法。
口腔微生物群变化与癌症之间的相互作用：口腔微生物群对癌症的发展可能产生重大影响。在人类口腔内，超过700种细菌的多样性令人印象深刻，使其成为体内第二大变化的微生物组。这种良好平衡的口腔微生物组生态系统对于维持口腔健康至关重要。然而,这种平衡的破坏，通常由饮食习惯和口腔卫生不足引起，会导致各种口腔疾病，如牙周炎，空腔,牙龈炎,甚至口腔癌。有令人信服的证据表明口腔微生物与几种类型的癌症有关，包括口服,胰腺,结直肠,肺，胃,头颈癌.这篇综述讨论了癌症与人类口腔微生物群成员之间的关键联系。在科学网进行了广泛的搜索，Scopus,和PubMed数据库提供了我们对口腔微生物群在各种人类癌症中的作用的理解的最新概述。通过了解致癌的可能的微生物起源，医疗保健专业人员可以更早地诊断肿瘤疾病，并相应地设计治疗方法。
