Abstract：
Individuals with Down syndrome are known to have a greater prevalence of ocular conditions such as strabismus, nystagmus, elevated refractive error, poor accommodative function, elevated higher-order optical aberrations and corneal abnormalities. Related to these conditions, individuals with Down syndrome commonly have reduced best-corrected visual acuity at both far and near viewing distances across their lifespan. This review summarises the various optical sources of visual acuity reduction in this population and describes clinical trials that have evaluated alternative spectacle prescribing strategies to minimise these optical deficits. Although refractive corrections may still have limitations in their ability to normalise visual acuity for individuals with Down syndrome, the current literature provides evidence for eye care practitioners to consider in their prescribing practices for this population to maximise visual acuity. These considerations include accounting for the presence of elevated higher-order aberrations when determining refractive corrections and considering bifocal lens prescriptions, even for young children with Down syndrome.
摘要：
已知患有唐氏综合症的人患有斜视等眼部疾病的患病率更高，眼球震颤,屈光不正升高,调节功能差，高阶光学像差升高和角膜异常。与这些条件有关,患有唐氏综合症的个体通常在其寿命中的远和近观看距离上都降低了最佳矫正视力。这篇综述总结了该人群中视力降低的各种光源，并描述了评估替代眼镜处方策略以最大程度地减少这些光学缺陷的临床试验。尽管屈光矫正可能在使唐氏综合症患者的视力正常化的能力方面仍然存在局限性，目前的文献为眼科保健医生在为该人群开处方时考虑最大限度地提高视力提供了证据.这些考虑因素包括在确定屈光矫正时考虑升高的高阶像差的存在，并考虑双焦点透镜处方，即使是患有唐氏综合症的幼儿。
