在肝细胞癌中靶向 Hippo / YAP1 信号通路 : 从机制到治疗药物 ( 综述 ) 。
关键词: Hippo pathway TAZ YAP1 cancer hepatocellular carcinoma
Mesh : Humans Carcinoma, Hepatocellular / drug therapy metabolism pathology Liver Neoplasms / drug therapy metabolism pathology Transcription Factors / metabolism Signal Transduction / drug effects Hippo Signaling Pathway YAP-Signaling Proteins / metabolism Adaptor Proteins, Signal Transducing / metabolism Protein Serine-Threonine Kinases / metabolism Tumor Microenvironment / drug effects Molecular Targeted Therapy / methods Antineoplastic Agents / therapeutic use pharmacology Gene Expression Regulation, Neoplastic / drug effects Cell Proliferation / drug effects Animals
来 源:
DOI:10.3892/ijo.2024.5676
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