PDF(Pubmed)
Abstract：
UNASSIGNED: In 2015, the National Institute of Dental and Craniofacial Research (NIDCR) launched the Multidisciplinary Collaborative Research Consortium to Reduce Oral Health Disparities in Children, supporting four randomized trials testing strategies to improve preventive care. A Coordinating Center provides scientific expertise, data acquisition and quality assurance services, safety monitoring, and final analysis-ready datasets. This paper describes the trials\' economic analysis strategies, placing these strategies within the broader context of contemporary economic analysis methods.
UNASSIGNED: The Coordinating Center established a Cost Collaborative Working Group to share information from the four trials about the components of their economic analyses. Study teams indicated data sources for their economic analysis using a set of structured tables. The Group meets regularly to share progress, discuss challenges, and coordinate analytic approaches.
UNASSIGNED: All four trials will calculate incremental cost-effectiveness ratios; two will also conduct cost-utility analyses using proxy diseases to estimate health state utilities. Each trial will consider at least two perspectives. Key process measures include dental services provided to child participants. The non-preference-weighted Early Childhood Oral Health Impact Scale (ECOHIS) will measure oral health-related quality of life. All trials are measuring training, implementation, personnel and supervision, service, supplies, and equipment costs.
UNASSIGNED: Consistent with best practices, all four trials have integrated economic analysis during their planning stages. This effort is critical since poor quality or absence of essential data can limit retrospective analysis. Integrating economic analysis into oral health preventive intervention research can provide guidance to clinicians and practices, payers, and policymakers.
UNASSIGNED: The Coordinating Center established a Cost Collaborative Working Group to share information from the four trials about the components of their economic analyses. Study teams indicated data sources for their economic analysis using a set of structured tables. The Group meets regularly to share progress, discuss challenges, and coordinate analytic approaches.
UNASSIGNED: All four trials will calculate incremental cost-effectiveness ratios; two will also conduct cost-utility analyses using proxy diseases to estimate health state utilities. Each trial will consider at least two perspectives. Key process measures include dental services provided to child participants. The non-preference-weighted Early Childhood Oral Health Impact Scale (ECOHIS) will measure oral health-related quality of life. All trials are measuring training, implementation, personnel and supervision, service, supplies, and equipment costs.
UNASSIGNED: Consistent with best practices, all four trials have integrated economic analysis during their planning stages. This effort is critical since poor quality or absence of essential data can limit retrospective analysis. Integrating economic analysis into oral health preventive intervention research can provide guidance to clinicians and practices, payers, and policymakers.
摘要：
■2015年，美国国家牙科和颅面研究所（NIDCR）成立了多学科合作研究联盟，以减少儿童的口腔健康差异，支持四项随机试验测试改善预防性护理的策略。协调中心提供科学专业知识，数据采集和质量保证服务，安全监测,和最终分析就绪数据集。本文介绍了试验的经济分析策略，将这些策略置于当代经济分析方法的更广泛背景下。
■协调中心成立了一个成本协作工作组，以共享来自四个试验的有关其经济分析组成部分的信息。研究小组使用一组结构化表格指出了其经济分析的数据来源。该小组定期开会，分享进展，讨论挑战,协调分析方法。
■所有四项试验都将计算增量成本效益比；两项还将使用代理疾病进行成本效用分析，以估计健康状态的效用。每个审判将考虑至少两个观点。关键的过程措施包括向儿童参与者提供牙科服务。非偏好加权早期儿童口腔健康影响量表（ECOHIS）将衡量口腔健康相关的生活质量。所有的试验都是衡量训练，实施，人员和监督，服务,用品,设备成本。
■符合最佳实践，所有四项试验都在规划阶段进行了综合经济分析。这项工作至关重要，因为质量差或缺乏必要数据会限制回顾性分析。将经济分析纳入口腔健康预防干预研究可以为临床医生和实践提供指导。付款人,和政策制定者。
■协调中心成立了一个成本协作工作组，以共享来自四个试验的有关其经济分析组成部分的信息。研究小组使用一组结构化表格指出了其经济分析的数据来源。该小组定期开会，分享进展，讨论挑战,协调分析方法。
■所有四项试验都将计算增量成本效益比；两项还将使用代理疾病进行成本效用分析，以估计健康状态的效用。每个审判将考虑至少两个观点。关键的过程措施包括向儿童参与者提供牙科服务。非偏好加权早期儿童口腔健康影响量表（ECOHIS）将衡量口腔健康相关的生活质量。所有的试验都是衡量训练，实施，人员和监督，服务,用品,设备成本。
■符合最佳实践，所有四项试验都在规划阶段进行了综合经济分析。这项工作至关重要，因为质量差或缺乏必要数据会限制回顾性分析。将经济分析纳入口腔健康预防干预研究可以为临床医生和实践提供指导。付款人,和政策制定者。
