UNASSIGNED: This retrospective cohort study, conducted at Baqai Institute of Diabetology and Endocrinology (BIDE), Baqai Medical University, Karachi, Pakistan (January 2022 - January 2023), focused on registered pregnancies of women with Type-1 diabetes. A predesigned questionnaire recorded demographic information, diabetes and obstetric history, clinical details, treatment specifics, maternal, perinatal, and neonatal outcomes.
UNASSIGNED: This study included 100 women with pre-existing Type-1 diabetes (mean age: 15.11 ± 5.64 years at diabetes diagnosis). Of these, 72% reported unplanned pregnancies, with a mean HbA1C at conception 8.29%. Median gestational age at delivery was 32.15 ± 10.82 weeks. Delivery outcomes included 40% normal vaginal deliveries and 60% C-sections (9% emergency, 51% elective). Stillbirths occurred in 14 cases, while 16 women experienced one miscarriage, seven had two, and 10 had three miscarriages. Glycemic targets (fasting) were achieved in 55 women, and post-meal targets only in 29, whereas, neonatal complications included hypoglycemia in 13 and low birth weight in 12 neonates.
UNASSIGNED: The high frequency of unplanned pregnancies and cesarean sections along with poor management of pre-pregnancy care and poor glycemic control results in compromised maternal and perinatal outcomes in this high-risk group.
■这项回顾性队列研究,在Baqai糖尿病和内分泌学研究所(BIDE)进行,巴凯医科大学,卡拉奇,巴基斯坦(2022年1月-2023年1月),重点关注1型糖尿病妇女的登记怀孕情况。预先设计的问卷记录了人口统计信息,糖尿病和产科史,临床细节,治疗细节,母性,围产期,和新生儿结局。
■这项研究包括100名预先存在1型糖尿病的女性(平均年龄:15.11±5.64岁的糖尿病诊断)。其中,72%的人报告了意外怀孕,受孕时平均HbA1C为8.29%。分娩时的中位胎龄为32.15±10.82周。分娩结果包括40%正常阴道分娩和60%剖腹产(9%急诊,51%选修)。14例发生死胎,16名妇女经历了一次流产,七个有两个,10人流产了3次.55名女性实现了血糖目标(禁食),和餐后目标只有29,而,新生儿并发症包括13例低血糖和12例新生儿低出生体重。
意外妊娠和剖宫产的频率高,孕前护理管理不善,血糖控制不佳,导致这一高危人群的孕产妇和围产期结局受损。