PDF(Pubmed)
Abstract：
UNASSIGNED: To investigate the pathogen distribution and clinical characteristics of acute community-acquired lower respiratory tract infections (CALRTIs).
UNASSIGNED: This was a retrospective study. The clinical data of 218 patients with CALRTIs admitted to Baoding No.1 Central Hospital from December 2021 to December 2022 were retrospectively collected and were divided into two groups according to the results of polymerase chain reaction(PCR) testing using a nasopharyngeal swab: streptococcus pneumoniae positive group(observation group) and non-streptococcus pneumoniae positive group(control group). Clinical symptoms, blood gas analysis indicators were compared between the two groups.
UNASSIGNED: Haemophilus influenzae and Staphylococcus aureus, as well as virus and atypical pathogen infection, were the predominant pathogenic bacteria in both groups. No statistically significant differences were observed in the positive rates of sputum smear, sputum culture, respiratory virus detection and atypical pathogen detection between the two groups(P>0.05). However, the control group had a higher detection rate of gram-positive bacteria, gram-negative bacteria and Legionella pneumophila in sputum smears than the observation group, with a statistically significant difference(P<0.05). One death occurred in each group, with no significant difference in mortality and six in each group left the hospital or were transferred due to deterioration, with no significant difference in improved discharge rates.
UNASSIGNED: Acute community-acquired lower respiratory tract infections(CALRTIs) take bacteria, viruses and atypical pathogens as its leading pathogenic bacteria. In the treatment of patients with acute CALRTIs, early pathogenic examination should be performed to assist in guiding antibiotic therapy for rapid control, early recovery and ameliorated clinical outcomes.
UNASSIGNED: This was a retrospective study. The clinical data of 218 patients with CALRTIs admitted to Baoding No.1 Central Hospital from December 2021 to December 2022 were retrospectively collected and were divided into two groups according to the results of polymerase chain reaction(PCR) testing using a nasopharyngeal swab: streptococcus pneumoniae positive group(observation group) and non-streptococcus pneumoniae positive group(control group). Clinical symptoms, blood gas analysis indicators were compared between the two groups.
UNASSIGNED: Haemophilus influenzae and Staphylococcus aureus, as well as virus and atypical pathogen infection, were the predominant pathogenic bacteria in both groups. No statistically significant differences were observed in the positive rates of sputum smear, sputum culture, respiratory virus detection and atypical pathogen detection between the two groups(P>0.05). However, the control group had a higher detection rate of gram-positive bacteria, gram-negative bacteria and Legionella pneumophila in sputum smears than the observation group, with a statistically significant difference(P<0.05). One death occurred in each group, with no significant difference in mortality and six in each group left the hospital or were transferred due to deterioration, with no significant difference in improved discharge rates.
UNASSIGNED: Acute community-acquired lower respiratory tract infections(CALRTIs) take bacteria, viruses and atypical pathogens as its leading pathogenic bacteria. In the treatment of patients with acute CALRTIs, early pathogenic examination should be performed to assist in guiding antibiotic therapy for rapid control, early recovery and ameliorated clinical outcomes.
摘要：
■探讨急性社区获得性下呼吸道感染（CALRTIs）的病原菌分布及临床特点。
■这是一项回顾性研究。回顾性收集2021年12月至2022年12月保定市第一中心医院收治的218例CALRTIs患者的临床资料，根据鼻咽拭子聚合酶链反应（PCR）检测结果分为两组：肺炎链球菌阳性组（观察组）和非肺炎链球菌阳性组（对照组）。临床症状,比较两组血气分析指标。
■流感嗜血杆菌和金黄色葡萄球菌，以及病毒和非典型病原体感染，是两组的主要致病菌。痰涂片阳性率差异无统计学意义,痰培养,两组呼吸道病毒检测和非典型病原体检测差异无统计学意义(P>0.05)。然而,对照组革兰阳性菌检出率较高,痰涂片中革兰阴性菌和嗜肺军团菌均优于观察组,差异具有统计学意义(P<0.05)。每组有一人死亡,死亡率无显著差异，每组6人出院或因病情恶化而转院，改善的放电率没有显着差异。
■急性社区获得性下呼吸道感染（CALRTIs）细菌，病毒和非典型病原体为其主要致病菌。在急性CALRTIs患者的治疗中，应进行早期致病性检查，以协助指导抗生素治疗以快速控制，早期恢复和改善临床结局。
■这是一项回顾性研究。回顾性收集2021年12月至2022年12月保定市第一中心医院收治的218例CALRTIs患者的临床资料，根据鼻咽拭子聚合酶链反应（PCR）检测结果分为两组：肺炎链球菌阳性组（观察组）和非肺炎链球菌阳性组（对照组）。临床症状,比较两组血气分析指标。
■流感嗜血杆菌和金黄色葡萄球菌，以及病毒和非典型病原体感染，是两组的主要致病菌。痰涂片阳性率差异无统计学意义,痰培养,两组呼吸道病毒检测和非典型病原体检测差异无统计学意义(P>0.05)。然而,对照组革兰阳性菌检出率较高,痰涂片中革兰阴性菌和嗜肺军团菌均优于观察组,差异具有统计学意义(P<0.05)。每组有一人死亡,死亡率无显著差异，每组6人出院或因病情恶化而转院，改善的放电率没有显着差异。
■急性社区获得性下呼吸道感染（CALRTIs）细菌，病毒和非典型病原体为其主要致病菌。在急性CALRTIs患者的治疗中，应进行早期致病性检查，以协助指导抗生素治疗以快速控制，早期恢复和改善临床结局。
