PDF(Pubmed)
Abstract：
UNASSIGNED: To explore the effect of Gegen Qinlian Decoction (GQD) combined with dietary management in the treatment of patients with Type-2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) (T2DM MetS).
UNASSIGNED: This is a retrospective analysis of 102 cases of T2DM in the Brain Hospital of Hunan Province, China from April 2020 to February 2023. Of them, 49 patients received conventional drug treatment (control group), and 53 patients received GQD combined with dietary management on the basis of conventional drugs (observation group). Treatment efficacy was calculated, and blood glucose levels before and after the treatment, blood lipid-related indicators, tumor necrosis factor-α (TNF-α) and adiponectin (ADP) levels, and incidence of adverse reactions were compared between the two groups.
UNASSIGNED: The total efficacy of the observation group (92.45%) was significantly higher than that of the control group (75.51%) (P<0.05). After the treatment, blood glucose and lipid indicators in both groups were significantly improved compared to pretreatment levels, and were significantly better in the observation group than in the control group (P<0.05). After the treatment, TNF-α levels in both groups decreased compared to before the treatment, and were significantly lower in the observation group compared to the control group. Levels of ADP after the treatment increased, and were significantly higher in the observation group compared to the control group (P<0.05).
UNASSIGNED: When taken as an adjunct to the conventional drug regimen, GQD combined with dietary management can effectively regulate blood glucose and lipid metabolism in patients with T2DM and MetS (T2DM MetS), improve TNF-α and ADP levels, and enhance disease treatment effectiveness.
UNASSIGNED: This is a retrospective analysis of 102 cases of T2DM in the Brain Hospital of Hunan Province, China from April 2020 to February 2023. Of them, 49 patients received conventional drug treatment (control group), and 53 patients received GQD combined with dietary management on the basis of conventional drugs (observation group). Treatment efficacy was calculated, and blood glucose levels before and after the treatment, blood lipid-related indicators, tumor necrosis factor-α (TNF-α) and adiponectin (ADP) levels, and incidence of adverse reactions were compared between the two groups.
UNASSIGNED: The total efficacy of the observation group (92.45%) was significantly higher than that of the control group (75.51%) (P<0.05). After the treatment, blood glucose and lipid indicators in both groups were significantly improved compared to pretreatment levels, and were significantly better in the observation group than in the control group (P<0.05). After the treatment, TNF-α levels in both groups decreased compared to before the treatment, and were significantly lower in the observation group compared to the control group. Levels of ADP after the treatment increased, and were significantly higher in the observation group compared to the control group (P<0.05).
UNASSIGNED: When taken as an adjunct to the conventional drug regimen, GQD combined with dietary management can effectively regulate blood glucose and lipid metabolism in patients with T2DM and MetS (T2DM MetS), improve TNF-α and ADP levels, and enhance disease treatment effectiveness.
摘要：
■探讨葛根芩连汤(GQD)联合饮食管理对2型糖尿病(T2DM)合并代谢综合征(T2DMMetS)患者的治疗效果。
■这是湖南省脑科医院102例2型糖尿病患者的回顾性分析,中国从2020年4月到2023年2月。其中,49例患者接受常规药物治疗(对照组),53例患者在常规药物治疗的基础上接受GQD联合饮食管理（观察组）。计算治疗效果，治疗前后的血糖水平，血脂相关指标，肿瘤坏死因子-α（TNF-α）和脂联素（ADP）水平，比较两组患者的不良反应发生率。
■观察组总有效率(92.45%)明显高于对照组(75.51%)(P<0.05)。治疗后,两组患者的血糖和血脂指标均较治疗前显著改善,观察组明显优于对照组(P<0.05)。治疗后,两组TNF-α水平均较治疗前有所下降,观察组明显低于对照组。治疗后ADP水平升高,观察组明显高于对照组(P<0.05)。
■当作为常规药物方案的辅助治疗时，GQD联合饮食管理可有效调节T2DM合并MetS(T2DMMetS)患者的糖脂代谢,改善TNF-α和ADP水平，提高疾病治疗效果。
■这是湖南省脑科医院102例2型糖尿病患者的回顾性分析,中国从2020年4月到2023年2月。其中,49例患者接受常规药物治疗(对照组),53例患者在常规药物治疗的基础上接受GQD联合饮食管理（观察组）。计算治疗效果，治疗前后的血糖水平，血脂相关指标，肿瘤坏死因子-α（TNF-α）和脂联素（ADP）水平，比较两组患者的不良反应发生率。
■观察组总有效率(92.45%)明显高于对照组(75.51%)(P<0.05)。治疗后,两组患者的血糖和血脂指标均较治疗前显著改善,观察组明显优于对照组(P<0.05)。治疗后,两组TNF-α水平均较治疗前有所下降,观察组明显低于对照组。治疗后ADP水平升高,观察组明显高于对照组(P<0.05)。
■当作为常规药物方案的辅助治疗时，GQD联合饮食管理可有效调节T2DM合并MetS(T2DMMetS)患者的糖脂代谢,改善TNF-α和ADP水平，提高疾病治疗效果。
