关键词: First trimester miscarriage Misoprostol Missed miscarriage management

来  源:   DOI:10.12669/pjms.40.7.8751   PDF(Pubmed)

Abstract:
UNASSIGNED: Miscarriage, a common complication of early pregnancy before 12 completed weeks of gestation, is typically managed medically. We aimed to estimate the success and complication rate of medical management in women with first-trimester missed miscarriages. Our objective was to calculate the rate of complete uterine evacuation within three weeks of treatment, rate of infection, significant blood loss, re-admission, or surgical evacuation.
UNASSIGNED: It was a retrospective cross-sectional study that included women diagnosed with miscarriage at less than 13 weeks\' gestation in Latifa Hospital\'s Gynecology Department from January 2019 to December 2019 in Dubai. These patients were given vaginal misoprostol, 400-800 mcg every 6-8 hours until expulsion of pregnancy.
UNASSIGNED: There were 294 women included in the study. The success rate was 60.5% (178/294). Twenty women developed significant blood loss (6.8%), four women developed infection (1.4%), 76 required readmission (25.9%), 12 women received blood transfusion (4.1%), and 74 women required a surgical evacuation (25.2%). Nulliparity, unscarred uterus, and the presence of abdominal pain with vaginal bleeding before treatment were significantly associated with the successful medical treatment (p<0.05).
UNASSIGNED: The success rate of the medical regimen studied lies on the lower end of what is quoted in the literature. The difference in the success rate could be attributed to the different definitions of success in other studies. Nulliparity, unscarred uterus and presence of abdominal pain with vaginal bleeding were associated with higher success.
摘要:
流产,妊娠12周之前的早期妊娠常见并发症,通常是医学管理。我们旨在评估妊娠早期流产妇女的医疗管理成功率和并发症发生率。我们的目标是计算治疗后三周内子宫完全排空率,感染率,大量失血,重新入场,或手术疏散。
这是一项回顾性横断面研究,包括2019年1月至2019年12月在迪拜Latifa医院妇科诊断为妊娠不到13周流产的妇女。这些患者给予阴道米索前列醇,400-800mcg每6-8小时,直到怀孕。
该研究包括294名女性。成功率为60.5%(178/294)。20名妇女出现严重失血(6.8%),四名妇女出现感染(1.4%),76要求再入院(25.9%),12名妇女接受了输血(4.1%),74名妇女需要手术后送(25.2%)。无效,无疤痕的子宫,治疗前腹痛伴阴道出血的存在与药物治疗的成功显著相关(p<0.05)。
所研究的医疗方案的成功率位于文献中引用的下限。成功率的差异可以归因于其他研究中对成功的不同定义。无效,无瘢痕子宫和腹痛伴阴道出血与较高的成功率相关.
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