关键词: Heart failure Maternal health Mortality Peripartum cardiomyopathy Pregnancy

来  源:   DOI:10.14740/jmc4228   PDF(Pubmed)

Abstract:
Peripartum cardiomyopathy (PPCM) poses a significant challenge in maternal health, characterized by heart failure with reduced ejection fraction during late pregnancy or early postpartum. Despite advances in understanding PPCM, it remains life-threatening with substantial maternal morbidity and mortality. This article reviews the epidemiology, etiology, diagnostic challenges, management strategies, and outcomes associated with PPCM. A case report of a 29-year-old woman with PPCM is presented, emphasizing the importance of early recognition and tailored management. The patient\'s presentation was marked by atypical symptoms, including dysuria, lumbar pain, persistent fever, and oral intake intolerance. Despite aggressive medical intervention, the patient experienced a tragic outcome, succumbing to cardiopulmonary arrest within 48 h of admission. This case underscores the challenges in diagnosing and managing PPCM, particularly when presenting with nonspecific symptoms and emphasizes the urgent need for improved diagnostic criteria and therapeutic interventions to mitigate adverse outcomes in affected individuals.
摘要:
围产期心肌病(PPCM)对孕产妇健康构成了重大挑战,以妊娠晚期或产后早期射血分数降低为特征的心力衰竭。尽管在理解PPCM方面取得了进展,它仍然危及生命,大量的孕产妇发病率和死亡率。本文回顾了流行病学,病因学,诊断挑战,管理策略,以及与PPCM相关的结果。介绍了一例29岁女性PPCM患者的病例报告,强调早期识别和量身定制管理的重要性。病人的表现有不典型的症状,包括排尿困难,腰椎疼痛,持续发烧,和口服摄入不耐受。尽管积极的医疗干预,病人经历了悲惨的结局,入院后48小时内死于心肺骤停。这个案例强调了诊断和管理PPCM的挑战,特别是当出现非特异性症状时,强调迫切需要改进诊断标准和治疗干预措施,以减轻受影响个体的不良结局。
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