PDF(Pubmed)
Abstract：
UNASSIGNED: Pregnancy-associated fulminant type 1 diabetes (PF) occurs during pregnancy or within 2 weeks of delivery. Although it occurs infrequently, it is associated with high fetal mortality rate. Few studies have examined whether PF is associated with gestational diabetes mellitus (GDM).
UNASSIGNED: A 29-year-old woman diagnosed with GDM at 24 weeks of gestation developed a fever, sore throat, nausea and vomiting at 29 weeks of gestation. Ketoacidosis was considered based on her blood ketone and glucose levels and the results of a blood gas analysis. Since the patient\'s islet function declined rapidly, fluid replacement, insulin therapy, and other treatments were administered. The patient was ultimately diagnosed with PF, and has required ongoing insulin therapy. She delivered a healthy baby girl by elective cesarean section at 37-week gestation. Her blood glucose has been satisfactorily controlled over the 12 months since her acute presentation.
UNASSIGNED: PF is characterized by poor maternal and infant outcomes and a high stillbirth rate. Blood glucose should be regularly monitored in pregnant women with GDM. A sudden increase in blood glucose may indicate the possibility of PF, which needs to be managed in a timely manner to avoid adverse pregnancy outcomes.
UNASSIGNED: A 29-year-old woman diagnosed with GDM at 24 weeks of gestation developed a fever, sore throat, nausea and vomiting at 29 weeks of gestation. Ketoacidosis was considered based on her blood ketone and glucose levels and the results of a blood gas analysis. Since the patient\'s islet function declined rapidly, fluid replacement, insulin therapy, and other treatments were administered. The patient was ultimately diagnosed with PF, and has required ongoing insulin therapy. She delivered a healthy baby girl by elective cesarean section at 37-week gestation. Her blood glucose has been satisfactorily controlled over the 12 months since her acute presentation.
UNASSIGNED: PF is characterized by poor maternal and infant outcomes and a high stillbirth rate. Blood glucose should be regularly monitored in pregnant women with GDM. A sudden increase in blood glucose may indicate the possibility of PF, which needs to be managed in a timely manner to avoid adverse pregnancy outcomes.
摘要：
■妊娠相关的暴发性1型糖尿病（PF）发生在怀孕期间或分娩后2周内。虽然它很少发生，它与高胎儿死亡率有关。很少有研究检查PF是否与妊娠糖尿病（GDM）有关。
一名29岁的女性在妊娠24周时被诊断为GDM，出现了发烧，喉咙痛,妊娠29周时恶心和呕吐。根据她的血酮和葡萄糖水平以及血气分析结果，认为酮症酸中毒。由于患者的胰岛功能迅速下降，补液,胰岛素治疗,和其他治疗。患者最终被诊断为PF，并且需要持续的胰岛素治疗。她在妊娠37周时通过选择性剖宫产分娩了一个健康的女婴。自急性发作以来的12个月中，她的血糖得到了令人满意的控制。
■PF的特点是母婴结局差，死胎率高。GDM孕妇应定期监测血糖。血糖突然升高可能表明PF的可能性，需要及时处理，以避免不良妊娠结局。
一名29岁的女性在妊娠24周时被诊断为GDM，出现了发烧，喉咙痛,妊娠29周时恶心和呕吐。根据她的血酮和葡萄糖水平以及血气分析结果，认为酮症酸中毒。由于患者的胰岛功能迅速下降，补液,胰岛素治疗,和其他治疗。患者最终被诊断为PF，并且需要持续的胰岛素治疗。她在妊娠37周时通过选择性剖宫产分娩了一个健康的女婴。自急性发作以来的12个月中，她的血糖得到了令人满意的控制。
■PF的特点是母婴结局差，死胎率高。GDM孕妇应定期监测血糖。血糖突然升高可能表明PF的可能性，需要及时处理，以避免不良妊娠结局。
