PDF(Pubmed)
Abstract：
UNASSIGNED: Metabolic associated fatty liver disease (MAFLD) stands as the leading cause of chronic liver disease globally. Notably, individuals with metabolic risk factors, such as diabetes and obesity, exhibit a staggering prevalence of MAFLD, with estimates reaching up to 70%. However, despite its widespread occurrence, there\'s a noticeable gap in understanding and awareness about MAFLD among these high-risk groups.
UNASSIGNED: The main objective of this study was to assess the awareness and prevalence of MAFLD among diabetic patients who regularly receive secondary care focusing particularly on how multiethnic backgrounds and associated lifestyle preferences influence these health outcomes.
UNASSIGNED: Cross-sectional study.
UNASSIGNED: Patients with type 2 diabetes (T2D) who regularly attend Lambeth Diabetes Intermediate Care Team clinics were invited to undergo MAFLD screening using FibroScan. Those who agreed to participate were provided with structured questionnaires on diet, physical activity, and MAFLD knowledge by a hepatologist. For each participant, anthropometric data, medical history, liver stiffness measurement, and controlled attenuation parameter (CAP) were documented. Steatosis was identified with a CAP value of ⩾275 dB/m, and advanced fibrosis was flagged at values of ⩾8 kPa.
UNASSIGNED: The FibroScan data was valid in 96.4% (215), 53.5% (115/215) had steatosis and 26.2% (58/215) had liver fibrosis in this multiethnic high-risk group. Awareness of MAFLD was notably low at 30.9%. Alarmingly, 69% of patients diagnosed with liver fibrosis were unfamiliar with the condition. Additionally, understanding of MAFLD showed variation among different ethnic groups with highest levels were demonstrated in the Caucasian/White population (46%). Majority (96%) of these subjects were receiving specific lifestyle advice from healthcare professionals due to metabolic conditions and comorbidities. However, most patients preferred diets that were rich in carbohydrates (65.8%) and only 43% subjects performed moderate exercise daily highlighting lack of understanding regarding MAFLD and lifestyle management.
UNASSIGNED: There\'s a pressing need for increased awareness of MAFLD, especially in multiethnic high-risk groups. Additionally, the development of cost-effective strategies to stratify risk is essential to address this growing health concern.
Ethnic differences and lack of awareness increase fatty liver disease risk in South London diabetics Metabolic associated fatty liver disease (MAFLD) or more commonly fatty liver disease is the leading cause of chronic liver disease globally, particularly affecting individuals with diabetes and obesity. This study focuses on patients with type 2 diabetes in South London who regularly receive secondary care, examining the awareness and prevalence of MAFLD, especially across different ethnic groups. Participants, all with Type 2 Diabetes, attended clinics run by the Diabetes Intermediate Care Team where they underwent MAFLD screening using Fibroscan. This tool measures liver stiffness (fibrosis) and fat levels. In addition to the scans, participants answered questions about their diet, physical activity, and knowledge of MAFLD. Key findings include a low overall awareness of MAFLD, with only about 30.9% of patients aware of the disease. Among those diagnosed with liver fibrosis, 69% were unfamiliar with the condition, indicating a significant awareness gap. Interestingly, awareness levels varied among ethnic groups, with Caucasian/white patients showing the highest awareness at 46%. Despite receiving lifestyle advice from health professionals, many participants preferred carbohydrate-rich diets and only a minority engaged in daily moderate exercise. This behaviour highlights a general lack of understanding about MAFLD and its management through lifestyle changes. The study concludes that there is a critical need to raise awareness about MAFLD among high-risk, multi-ethnic groups in South London. It also highlights the necessity for developing cost-effective strategies to better identify and manage this growing health concern.
UNASSIGNED: The main objective of this study was to assess the awareness and prevalence of MAFLD among diabetic patients who regularly receive secondary care focusing particularly on how multiethnic backgrounds and associated lifestyle preferences influence these health outcomes.
UNASSIGNED: Cross-sectional study.
UNASSIGNED: Patients with type 2 diabetes (T2D) who regularly attend Lambeth Diabetes Intermediate Care Team clinics were invited to undergo MAFLD screening using FibroScan. Those who agreed to participate were provided with structured questionnaires on diet, physical activity, and MAFLD knowledge by a hepatologist. For each participant, anthropometric data, medical history, liver stiffness measurement, and controlled attenuation parameter (CAP) were documented. Steatosis was identified with a CAP value of ⩾275 dB/m, and advanced fibrosis was flagged at values of ⩾8 kPa.
UNASSIGNED: The FibroScan data was valid in 96.4% (215), 53.5% (115/215) had steatosis and 26.2% (58/215) had liver fibrosis in this multiethnic high-risk group. Awareness of MAFLD was notably low at 30.9%. Alarmingly, 69% of patients diagnosed with liver fibrosis were unfamiliar with the condition. Additionally, understanding of MAFLD showed variation among different ethnic groups with highest levels were demonstrated in the Caucasian/White population (46%). Majority (96%) of these subjects were receiving specific lifestyle advice from healthcare professionals due to metabolic conditions and comorbidities. However, most patients preferred diets that were rich in carbohydrates (65.8%) and only 43% subjects performed moderate exercise daily highlighting lack of understanding regarding MAFLD and lifestyle management.
UNASSIGNED: There\'s a pressing need for increased awareness of MAFLD, especially in multiethnic high-risk groups. Additionally, the development of cost-effective strategies to stratify risk is essential to address this growing health concern.
Ethnic differences and lack of awareness increase fatty liver disease risk in South London diabetics Metabolic associated fatty liver disease (MAFLD) or more commonly fatty liver disease is the leading cause of chronic liver disease globally, particularly affecting individuals with diabetes and obesity. This study focuses on patients with type 2 diabetes in South London who regularly receive secondary care, examining the awareness and prevalence of MAFLD, especially across different ethnic groups. Participants, all with Type 2 Diabetes, attended clinics run by the Diabetes Intermediate Care Team where they underwent MAFLD screening using Fibroscan. This tool measures liver stiffness (fibrosis) and fat levels. In addition to the scans, participants answered questions about their diet, physical activity, and knowledge of MAFLD. Key findings include a low overall awareness of MAFLD, with only about 30.9% of patients aware of the disease. Among those diagnosed with liver fibrosis, 69% were unfamiliar with the condition, indicating a significant awareness gap. Interestingly, awareness levels varied among ethnic groups, with Caucasian/white patients showing the highest awareness at 46%. Despite receiving lifestyle advice from health professionals, many participants preferred carbohydrate-rich diets and only a minority engaged in daily moderate exercise. This behaviour highlights a general lack of understanding about MAFLD and its management through lifestyle changes. The study concludes that there is a critical need to raise awareness about MAFLD among high-risk, multi-ethnic groups in South London. It also highlights the necessity for developing cost-effective strategies to better identify and manage this growing health concern.
摘要：
■代谢相关的脂肪肝（MAFLD）是全球慢性肝病的主要原因。值得注意的是,有代谢危险因素的个体，比如糖尿病和肥胖症，表现出惊人的MAFLD患病率，估计达到70%。然而,尽管它普遍存在，这些高危人群对MAFLD的理解和认识存在明显差距。
本研究的主要目的是评估经常接受二级护理的糖尿病患者对MAFLD的认识和患病率，特别是多种族背景和相关的生活方式偏好如何影响这些健康结果。
■横断面研究。
■定期参加兰贝斯糖尿病中级护理团队诊所的2型糖尿病（T2D）患者被邀请使用FibroScan进行MAFLD筛查。那些同意参加的人获得了关于饮食的结构化问卷，身体活动,和肝脏学家的MAFLD知识。对于每个参与者，人体测量数据,病史,肝脏硬度测量，并记录受控衰减参数(CAP)。脂肪变性被鉴定为CAP值为275dB/m，和晚期纤维化被标记为8kPa的值。
■FibroScan数据的有效期为96.4%（215），53.5％（115/215）有脂肪变性和26.2％（58/215）肝纤维化在这个多种族高危人群。MAFLD的知晓率明显较低，为30.9%。令人震惊的是,69%诊断为肝纤维化的患者不熟悉这种情况。此外,对MAFLD的了解显示不同种族之间的差异，在白种人/白人人群中表现出最高水平（46％）。由于代谢状况和合并症，这些受试者中的大多数（96％）正在接受医疗保健专业人员的特定生活方式建议。然而,大多数患者更喜欢富含碳水化合物的饮食(65.8%),只有43%的受试者每天进行适度运动,这凸显了对MAFLD和生活方式管理缺乏了解.
■迫切需要提高对MAFLD的认识，特别是在多种族高危人群中。此外,制定具有成本效益的风险分层策略对于解决这一日益增长的健康问题至关重要.
种族差异和缺乏意识会增加伦敦南部糖尿病患者的脂肪肝疾病风险代谢相关脂肪肝疾病（MAFLD）或更常见的脂肪肝疾病是全球慢性肝病的主要原因，特别影响糖尿病和肥胖症患者。这项研究的重点是伦敦南部定期接受二级护理的2型糖尿病患者，检查MAFLD的意识和患病率，尤其是在不同的种族群体中。参与者,都是2型糖尿病患者,参加了由糖尿病中级护理团队运营的诊所,他们使用Fibroscan进行了MAFLD筛查.该工具测量肝脏硬度（纤维化）和脂肪水平。除了扫描，参与者回答了关于他们饮食的问题，身体活动,和MAFLD的知识。主要发现包括对MAFLD的整体认识较低，只有约30.9%的患者知道这种疾病。在那些被诊断为肝纤维化的人中，69%的人不熟悉这种情况，表明存在明显的意识差距。有趣的是,各民族的认识水平各不相同，白种人/白人患者的认知度最高，为46％。尽管收到了健康专业人士的生活方式建议，许多参与者更喜欢富含碳水化合物的饮食，只有少数人每天进行适度运动。这种行为凸显了人们对MAFLD及其通过改变生活方式进行管理的普遍缺乏了解。该研究得出的结论是，迫切需要提高高危人群对MAFLD的认识，伦敦南部的多族裔群体。它还强调了制定具有成本效益的战略以更好地识别和管理这一日益严重的健康问题的必要性。
本研究的主要目的是评估经常接受二级护理的糖尿病患者对MAFLD的认识和患病率，特别是多种族背景和相关的生活方式偏好如何影响这些健康结果。
■横断面研究。
■定期参加兰贝斯糖尿病中级护理团队诊所的2型糖尿病（T2D）患者被邀请使用FibroScan进行MAFLD筛查。那些同意参加的人获得了关于饮食的结构化问卷，身体活动,和肝脏学家的MAFLD知识。对于每个参与者，人体测量数据,病史,肝脏硬度测量，并记录受控衰减参数(CAP)。脂肪变性被鉴定为CAP值为275dB/m，和晚期纤维化被标记为8kPa的值。
■FibroScan数据的有效期为96.4%（215），53.5％（115/215）有脂肪变性和26.2％（58/215）肝纤维化在这个多种族高危人群。MAFLD的知晓率明显较低，为30.9%。令人震惊的是,69%诊断为肝纤维化的患者不熟悉这种情况。此外,对MAFLD的了解显示不同种族之间的差异，在白种人/白人人群中表现出最高水平（46％）。由于代谢状况和合并症，这些受试者中的大多数（96％）正在接受医疗保健专业人员的特定生活方式建议。然而,大多数患者更喜欢富含碳水化合物的饮食(65.8%),只有43%的受试者每天进行适度运动,这凸显了对MAFLD和生活方式管理缺乏了解.
■迫切需要提高对MAFLD的认识，特别是在多种族高危人群中。此外,制定具有成本效益的风险分层策略对于解决这一日益增长的健康问题至关重要.
种族差异和缺乏意识会增加伦敦南部糖尿病患者的脂肪肝疾病风险代谢相关脂肪肝疾病（MAFLD）或更常见的脂肪肝疾病是全球慢性肝病的主要原因，特别影响糖尿病和肥胖症患者。这项研究的重点是伦敦南部定期接受二级护理的2型糖尿病患者，检查MAFLD的意识和患病率，尤其是在不同的种族群体中。参与者,都是2型糖尿病患者,参加了由糖尿病中级护理团队运营的诊所,他们使用Fibroscan进行了MAFLD筛查.该工具测量肝脏硬度（纤维化）和脂肪水平。除了扫描，参与者回答了关于他们饮食的问题，身体活动,和MAFLD的知识。主要发现包括对MAFLD的整体认识较低，只有约30.9%的患者知道这种疾病。在那些被诊断为肝纤维化的人中，69%的人不熟悉这种情况，表明存在明显的意识差距。有趣的是,各民族的认识水平各不相同，白种人/白人患者的认知度最高，为46％。尽管收到了健康专业人士的生活方式建议，许多参与者更喜欢富含碳水化合物的饮食，只有少数人每天进行适度运动。这种行为凸显了人们对MAFLD及其通过改变生活方式进行管理的普遍缺乏了解。该研究得出的结论是，迫切需要提高高危人群对MAFLD的认识，伦敦南部的多族裔群体。它还强调了制定具有成本效益的战略以更好地识别和管理这一日益严重的健康问题的必要性。
