Abstract:
An additional microscopic diagnostic sign has been identified for verification of asphyxial type of drowning. In white non-linear male rats (age 2 months) subjected to free drowning, significant hyperplasia of argyrophilic and morphofunctional activity of serotonin-containing APUD-cells of the laryngeal mucosa were revealed under conditions of acute anoxia in comparison with the intact control. These changes promote the development of laryngospasm, which prevents water penetration into the airways and lungs in asphyxial type of drowning. The presence of statistically significant hyperplasia of argyrophilic and morphofunctional activity of serotonin-containing APUD-cells of the laryngeal mucosa under conditions of acute anoxia can be used as an additional diagnostic criterion for asphyxial type of drowning in experimental studies.
摘要:
已经确定了另一个显微镜诊断标志,用于验证窒息类型的溺水。在遭受自由溺水的白色非线性雄性大鼠(2个月大)中,与完整对照相比,在急性缺氧条件下,喉粘膜含5-羟色胺的APUD细胞的嗜银和形态功能活性显着增生。这些变化促进了喉痉挛的发展,在窒息型溺水时防止水渗入气道和肺部。在急性缺氧条件下,喉粘膜中含5-羟色胺的APUD细胞的嗜银和形态功能活性的统计学显着增生可用作实验研究中窒息型溺水的额外诊断标准。