Abstract：
Lichen sclerosus (LS) is a chronic inflammatory dermatosis primarily affecting the genitalia, commonly characterized by pearly-white papules and plaques. Although predominantly affecting females, LS can manifest across all age groups, with a bimodal distribution observed in prepubescent girls and postmenopausal women. This case report presents an unusual instance of exclusive extragenital LS in a 10-year-old girl, showcasing hyperpigmented patches and wrinkled plaques resembling lichen planus on her forearms and lower legs. Histopathological analysis confirmed LS, revealing distinctive epidermal changes and lymphocytic infiltrates. The absence of mucosal involvement and unique clinical presentation differentiated this case from typical LS manifestations. Treatment with topical clobetasol propionate demonstrated significant improvement in pruritus. Extragenital LS is infrequent, particularly among children, and its diagnosis necessitates a comprehensive clinicopathological correlation. The reported case contributes valuable insights into this uncommon variant, emphasizing the importance of accurate diagnosis and tailored treatment strategies. Additionally, it highlights the efficacy of high-potency topical corticosteroids in managing this condition.
摘要：
硬化性苔藓（LS）是一种主要影响生殖器的慢性炎症性皮肤病，通常特征为珍珠白色丘疹和斑块。虽然主要影响女性，LS可以在所有年龄组中出现，在青春期前女孩和绝经后妇女中观察到双峰分布。此病例报告显示了一名10岁女孩的特殊性外LS，在她的前臂和小腿上展示了类似扁平苔藓的色素沉着斑块和皱纹斑块。组织病理学分析证实LS，揭示独特的表皮变化和淋巴细胞浸润。没有粘膜受累和独特的临床表现将该病例与典型的LS表现区分开。局部用丙酸氯倍他索治疗显示瘙痒的显着改善。婚外LS很少见，特别是在儿童中，其诊断需要综合的临床病理相关性。报告的病例为这种罕见的变异提供了宝贵的见解，强调准确诊断和量身定制治疗策略的重要性。此外,它强调了高效外用皮质类固醇治疗这种疾病的疗效.
