Abstract：
The incidence of early-onset colorectal cancer has been rising over the last two decades. Tumors in young patients have distinct features compared to older patients. They predominantly arise in the distal colon and rectum and have poor histological features. Patients tend to present at a more advanced stage and be exposed to more aggressive management approaches; however, this has not translated into a significant survival benefit compared to their older counterparts. This chapter will share current evidence on risk factors and management options for early onset colorectal cancer with a focus on rectal cancer.
摘要：
在过去的二十年中，早发性结直肠癌的发病率一直在上升。与老年患者相比，年轻患者的肿瘤具有明显的特征。它们主要出现在远端结肠和直肠，组织学特征差。患者往往表现在更晚期，并暴露于更积极的管理方法；然而，与老年人相比，这并没有转化为显著的生存获益。本章将分享有关早发性结直肠癌的风险因素和管理选择的最新证据，重点是直肠癌。
