Abstract:
Empirical findings suggested that anhedonia, a reduced capability to access pleasure and a core symptom in both schizophrenia and the major depressive disorder, can be present in people with high levels of social anhedonia and people with subsyndromal depression. Few studies have adopted a multidimensional framework to investigate anhedonia in these subclinical samples. We recruited 35 participants with high social anhedonia (SA), 53 participants with subsyndromal depression (SD), 20 participants with co-occurrence of both traits (CO), and 47 participants with low levels of both traits (CN) to complete a self-report questionnaire capturing the pleasure experience, and the Monetary Incentives Delay (MID) Task and the Social Incentives Delay (SID) Task capturing the motivation of reward. Results indicated that people with SA, SD and CO exhibited lower abstract anticipatory pleasure compared to CN. Moreover, people with SD and CO exhibited specific impairment in response to social incentives. Together, our findings characterized the multidimensional features of anhedonia performances of subclinical samples with SA, SD and CO, which may contribute to the formulation of early identification of at-risk groups.
摘要:
实证研究结果表明,快感缺失,精神分裂症和重度抑郁症的核心症状和获得快感的能力下降,可能存在于患有高度社会快感障碍的人和患有亚综合征抑郁症的人中。很少有研究采用多维框架来研究这些亚临床样本中的快感缺失。我们招募了35名具有高社会快感(SA)的参与者,53名患有亚综合征抑郁症(SD)的参与者,20名同时存在两种特征(CO)的参与者,和47名这两种特征(CN)水平较低的参与者完成一份自我报告问卷,捕捉快乐体验,货币激励延迟(MID)任务和社会激励延迟(SID)任务捕获奖励的动机。结果表明,患有SA的人,与CN相比,SD和CO表现出较低的抽象预期愉悦。此外,SD和CO患者在社会激励下表现出特定的损害。一起,我们的发现表征了SA亚临床样本的快感缺失表现的多维特征,SD和CO,这可能有助于早期识别高危人群。