Abstract：
The overuse of quinolone antibiotics has led to a series of health and environmental issues. Herein, we combine the distinct luminescence properties of Eu3+ with the unique structure of covalent organic frameworks (COFs) to develop a precise and sensitive fluorescent probe for detecting Flumequine (Flu) in water. Eu3+ is thoroughly anchored into the channels of COFs as recognition sites, while the synthesized probe material still maintains its intact framework structure. The unique structure of COFs provides excellent support and protection for Eu3+. Therefore, COF-Eu can rapidly bind with Flu which can transfer the absorbed energy to Eu3+ through an \"antenna effect\", resulting in red fluorescence. Moreover, there is a good linear relationship between Flu concentration in the range of 0-30 µM, with a detection limit of 41 nM. Simultaneously, the material maintains remarkable reproducibility, with its performance remaining almost unchanged after five cycles of use. Remarkably, the probe demonstrates excellent Flu recovery rates in real samples. This study provides a viable approach for the recognition of flumequine in the environment through a customized fluorescence detection method.
摘要：
喹诺酮类抗生素的过度使用导致了一系列的健康和环境问题。在这里，我们将Eu3的独特发光特性与共价有机骨架（COFs）的独特结构相结合，开发了一种精确而灵敏的荧光探针，用于检测水中的氟甲喹（Flu）。Eu3+作为识别位点被彻底锚定到COF的通道中，而合成的探针材料仍然保持其完整的框架结构。COFs独特的结构为Eu3+提供了极好的支持和保护。因此,COF-Eu可以迅速与流感结合，流感可以通过“天线效应”将吸收的能量转移到Eu3+，产生红色荧光。此外，在0-30µM范围内，流感浓度之间存在良好的线性关系，检测限为41nM。同时,该材料保持显著的再现性，其性能保持几乎不变后五个周期的使用。值得注意的是,该探针在实际样品中表现出优异的流感回收率。本研究通过定制的荧光检测方法为环境中氟甲喹的识别提供了可行的方法。
