PDF(Pubmed)
Abstract：
BACKGROUND: Chronic cough (persisting for ≥8 weeks) is a common disorder affecting approximately 5 to 10% of adults worldwide that is sometimes refractory to treatment (refractory chronic cough [RCC]) or has no identifiable cause (unexplained chronic cough [UCC]). There is minimal information on the patient\'s experience of RCC/UCC in Canada. The aim of this study was to evaluate the patient journey and perceptions related to RCC/UCC management in Canada.
METHODS: Our exploratory study included Canadians in the Leger Opinion Panel and focused on individuals with RCC or UCC. Key entry criteria were: age ≥18 years, cough on most days for ≥8 weeks, no smoking within 1 year, no serious respiratory disease or lung cancer, and not taking angiotensin-converting enzyme inhibitors. Individuals who met entry criteria were invited to complete an approximately 30-minute online survey with questions on demographic characteristics, healthcare professional (HCP) interactions, diagnosis of underlying conditions, current treatments, and satisfaction with HCPs and chronic cough therapies.
RESULTS: A total of 49,076 individuals completed the chronic cough screening questionnaire (July 30, 2021 to September 1, 2021): 1,620 (3.3%) met entry criteria for RCC or UCC, and 1,046 (2.1%) completed the online survey (mean age of 45 years, 61% female). Most respondents (58%) reported their chronic cough was managed by a general practitioner (GP). Forty-four percent of respondents did not have a diagnosis of an underlying condition for their cough. Breathing tests (39%) and chest imaging (34%) were the most common diagnostic tests. Cough suppressants (18%) were the most frequent current treatment. Respondents were moderately satisfied with their HCPs, but more than half considered their treatment ineffective and 34% had considered no longer seeking medical attention because of a lack of treatment success.
CONCLUSIONS: Individuals with RCC/UCC in Canada are largely unsatisfied with the effectiveness of treatment. Additional HCP education and new treatment options are needed to improve patient satisfaction.
METHODS: Our exploratory study included Canadians in the Leger Opinion Panel and focused on individuals with RCC or UCC. Key entry criteria were: age ≥18 years, cough on most days for ≥8 weeks, no smoking within 1 year, no serious respiratory disease or lung cancer, and not taking angiotensin-converting enzyme inhibitors. Individuals who met entry criteria were invited to complete an approximately 30-minute online survey with questions on demographic characteristics, healthcare professional (HCP) interactions, diagnosis of underlying conditions, current treatments, and satisfaction with HCPs and chronic cough therapies.
RESULTS: A total of 49,076 individuals completed the chronic cough screening questionnaire (July 30, 2021 to September 1, 2021): 1,620 (3.3%) met entry criteria for RCC or UCC, and 1,046 (2.1%) completed the online survey (mean age of 45 years, 61% female). Most respondents (58%) reported their chronic cough was managed by a general practitioner (GP). Forty-four percent of respondents did not have a diagnosis of an underlying condition for their cough. Breathing tests (39%) and chest imaging (34%) were the most common diagnostic tests. Cough suppressants (18%) were the most frequent current treatment. Respondents were moderately satisfied with their HCPs, but more than half considered their treatment ineffective and 34% had considered no longer seeking medical attention because of a lack of treatment success.
CONCLUSIONS: Individuals with RCC/UCC in Canada are largely unsatisfied with the effectiveness of treatment. Additional HCP education and new treatment options are needed to improve patient satisfaction.
摘要：
背景：慢性咳嗽（持续≥8周）是一种常见疾病，影响全球约5％至10％的成年人，有时难以治疗（难治性慢性咳嗽[RCC]）或没有可识别的原因（无法解释的慢性咳嗽[UCC]）。在加拿大，关于患者RCC/UCC经验的信息很少。这项研究的目的是评估与加拿大RCC/UCC管理相关的患者旅程和看法。
方法：我们的探索性研究包括Leger意见小组中的加拿大人，重点研究患有RCC或UCC的个体。主要进入标准为：年龄≥18岁，大多数天咳嗽≥8周，1年内不吸烟,没有严重的呼吸道疾病或肺癌，不服用血管紧张素转换酶抑制剂.符合入学标准的个人被邀请完成大约30分钟的在线调查，并提出有关人口统计特征的问题。医疗保健专业人员(HCP)互动，潜在疾病的诊断，目前的治疗方法，以及对HCPs和慢性咳嗽疗法的满意度。
结果：共有49,076人完成了慢性咳嗽筛查问卷（2021年7月30日至2021年9月1日）：1,620（3.3％）符合RCC或UCC的入选标准，和1046（2.1％）完成了在线调查（平均年龄45岁，61%女性）。大多数受访者（58％）报告他们的慢性咳嗽由全科医生（GP）管理。44％的受访者没有诊断出咳嗽的潜在疾病。呼吸测试（39%）和胸部成像（34%）是最常见的诊断测试。咳嗽抑制剂（18％）是目前最常见的治疗方法。受访者对他们的HCP感到适度满意，但超过一半的人认为他们的治疗无效，34%的人认为由于缺乏治疗成功而不再寻求医疗救助。
结论：在加拿大患有RCC/UCC的个体对治疗的有效性不满意。需要额外的HCP教育和新的治疗方案来提高患者满意度。
方法：我们的探索性研究包括Leger意见小组中的加拿大人，重点研究患有RCC或UCC的个体。主要进入标准为：年龄≥18岁，大多数天咳嗽≥8周，1年内不吸烟,没有严重的呼吸道疾病或肺癌，不服用血管紧张素转换酶抑制剂.符合入学标准的个人被邀请完成大约30分钟的在线调查，并提出有关人口统计特征的问题。医疗保健专业人员(HCP)互动，潜在疾病的诊断，目前的治疗方法，以及对HCPs和慢性咳嗽疗法的满意度。
结果：共有49,076人完成了慢性咳嗽筛查问卷（2021年7月30日至2021年9月1日）：1,620（3.3％）符合RCC或UCC的入选标准，和1046（2.1％）完成了在线调查（平均年龄45岁，61%女性）。大多数受访者（58％）报告他们的慢性咳嗽由全科医生（GP）管理。44％的受访者没有诊断出咳嗽的潜在疾病。呼吸测试（39%）和胸部成像（34%）是最常见的诊断测试。咳嗽抑制剂（18％）是目前最常见的治疗方法。受访者对他们的HCP感到适度满意，但超过一半的人认为他们的治疗无效，34%的人认为由于缺乏治疗成功而不再寻求医疗救助。
结论：在加拿大患有RCC/UCC的个体对治疗的有效性不满意。需要额外的HCP教育和新的治疗方案来提高患者满意度。
